Sindrome Cardiorenal
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Síndrome cardiorrenal Andrés Buitrago Maldonado
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El síndrome cardiorrenal (SCR) es una situación de afectación de
ambos órganos (Corazón y riñón) en que se potencian sus efectos
deletéreos de forma que el daño renal y el miocárdico progresan de
forma acelerada y retroalimentándose
Sociedad Española de Nefrología; Nefrología (2008) Supl. 3, 29-32
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International Journal of Nephrology Volume 2011, Article ID 920195, 11 pages
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CRS Type 1Pathophysiological interactions between heart and kidney in type 1 cardiorenal syndrome (CRS) or “acute CRS” (abrupt worsening of cardiac function, e.g., acute cardiogenic shock or acute decompensation of chronic heart failure) leading to kidney injury. ACE = angiotensin-converting enzyme; ANP = atrial natriuretic peptide; BNP = B-type (Brain) natriuretic peptide; CO = cardiac output; GFR = glomerular filtration rate; KIM = kidney injury molecule; N-GAL = neutrophil gelatinase-associated lipocalin; RAA = renin angiotensin aldosterone.
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Figure 2 CRS Type 2 Pathophysiological interactions between heart and kidney in type 2 cardiorenal syndrome (CRS) or “chronic CRS” (chronic abnormalities in cardiac function, e.g., chronic heart failure) causing progressive chronic kidney disease (CKD). F...
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CRS Type 3Pathophysiological interactions between heart and kidney in type 3 CRS or “acute renocardiac syndrome” (abrupt worsening of renal function, e.g., acute kidney failure or glomerulonephritis) causing acute cardiac disorder (e.g., heart failure, arrhythmia, pulmonary edema). MPO = myeloperoxidase; other abbreviations as in Figure 1.
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CRS Type4 Pathophysiological interactions between heart and kidney in type 4 cardiorenal syndrome (CRS) or “chronic renocardiac syndrome” (chronic kidney disease [CKD], e.g., chronic glomerular disease, contributing to decreased cardiac function, cardiac hypertrophy, or increased risk of adverse cardiovascular events). BMI = body mass index; EPO = erythropoietin; LDL = low-density lipoprotein.
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CRS Type 5 Pathophysiological interactions between heart and kidney in type 5 cardiorenal syndrome (CRS) or “secondary CRS” (systemic condition, e.g., diabetes mellitus, sepsis, causing both cardiac and renal dysfunction). LPS = lipopolysaccharide (endotoxin); RVR = renal vascular resistance.
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Bibliografía Journal of the American College of Cardiology Vol. 52, No. 19, 2008 ©
2008 by the American College of Cardiology Foundation ISSN 0735-1097/08/$34.00 Published by Elsevier Inc. doi:10.1016/j.jacc.2008.07.051
The Cardiorenal Syndrome: A Review; B. N. Shah and K. Greaves; International Journal of Nephrology Volume 2011, Article ID 920195, 11 pages doi:10.4061/2011/920195
Epidemiology of cardio-renal syndromes: workgroup statements fromthe 7th ADQI Consensus Conference; Sean M. Bagshaw, et al; Nephrol Dial Transplant (2010) 25: 1406–1416 doi: 10.1093/ndt/gfq066.
Síndrome cardio-renal: diagnóstico y tratamiento; Segovia, E. Medwave 2011 May;11(05):e5028 doi: 10.5867/medwave.2011.05.5028
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Gracias