Struktur Protein Kuartener

7/24/2019 Struktur Protein Kuartener

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B Y :

N I K K O M A R T H E N M A M B O R A N ( 1 5 0 9 0 0 5 0 7 7 )

M U HA M MA D A L FI A N DI N IK A ( 1 5 09 0 05 0 78 )

N I S A M A H A R A N I ( 1 5 0 9 0 0 5 0 7 9 )

R A H M I M A U L I D Y A P U T R A N T Y ( 1 5 0 9 0 0 5 0 8 0 )

THE QUATERNARY

STRUCTURE OF PROTEIN

B I O K I M I A V E T E R I N E R I

F A K U LT A S K E D O K T E R A N H E W A N

U N I V E R S I T A S U D A Y A N A


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The 3D Structure of Protein

There are 4 structure of rotein! such us" pri!r" #$r%&$%r'!#'&*!r" #$r%&$%r'! $'r$i!r" #$r%&$%r'! an# +%!$'r!r"#$r%&$%r'$

%$ The ri&ar' structure of a rotein is the secific se(uence of

a&ino aci#s$)$ The secon#ar' structure is the satia* arran+e&ent of a&ino

aci#s foun# in c*ose ro,i&it' on the o*'eti#e chain$

3$ The tertiar' stucture is a #escrition of the co&*e, an#

irre+u*ar fo*#in+ of the eti#e chain in three #i&ensions$


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The 3D Structure of Protein


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In so&e cases! *ar+e rotein can actua**' consist of t-o or &oreo*'eti#e chains$ Quaternar' structure refers to the -a's in-hich these o*'eti#es interact -ith one another$

Ho- a.out the (uaternar' structure/


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DI0ER/

A #i&er is the si&*est case of (uarterinar'structure$ In a #i&er! the are t-o o*ieti#es thatconstitute the rotein$ 1enera**'! each in#i2i#ua*

o*'eti#e is ca**e# su. unit$

These su. units are usua**' he*# to+ether .' nonco2a*ent .on#s .ut can a*so .e he*# .' co2a*ent

.on#s such us #isu*fi#e .ri#+es$


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Cate+ories of Protein -ith Quaternar' Structure

There are t-o &aor cate+ories of roteins -ith (uaternar'structure$

15O6U5ARPROTEIN

FI6ROUSPROTEINS


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1*o.u*ar Protein


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Fi.rous Protein


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1*o.u*ar 2s Fi.rous


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Fi.rous Proteins

These *ar+e rotein for& *on+ fi.ers an# *a' astructura* ro*e$ 7eratin an# co**a+en are t-oe,a&*es of fi.rous roteins$


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87eratin is the &aor co&onent of hair an# itconsist of t-o o*'eti#e su. units$ These su. unitsconsist of ri+hthan#e# 8he*ices that intert-ine tofor& a *efthan#e# suercoi* ca**e# the 8coi*e# coi*$

These t-o su. units are he*# to+ether .'"

%$ 9an #er :a**s forces

)$ Disu*fi#e .on#s


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1*o.u*ar Proteins

These roteins ha2e a -i#e ran+e of functions an# are re*ati2e*'sherica* in shae$ So&e e,a&*es inc*u#e he&o+*o.in! insu*in!DNA! o*'&erase! etc$

He&o+*o.in is tetra&er

that consist of fourin#i2i#ua* su. units$

Each su. unit is e(uie#-ith a he&e +rou that iscaa.*e of .in#in+ an

o,'+en &o*ecu*es$

Struktur Protein Kuartener

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