Iopromide
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Reactions 1452 - 18 May 2013 S Iopromide Transient cortical blindness: case report A 32-year-old man developed transient cortical blindness after receiving iopromide [Ultravist] as a contrast agent for coronary angiography. The man was suspected to have Brugada syndrome, and underwent coronary angiography conducted through the femoral artery with about 100mL of iopromide used as contrast agent [route and time to reaction onset not stated]. During the procedure, he reported visual impairment with no other focal symptoms. He completely lost his vision within 15 minutes. He remained haemodynamically stable, and was conscious with good verbal contact for the remainder of the coronary angiography. Immediately after the procedure, the man underwent ophthalmological and neurological consultation. There were no abnormalities detected other than binocular blindness. A CT scan of the head did not show any pathology. His visual impairment completely resolved the first day after the coronary angioplasty. He was discharged home on the third day in a good general condition with no symptoms. Author comment: "Transient cortical visual impairment is a rare, rapidly progressing complication of angiography. Although the exact mechanism of cortical visual impairment is unknown, the interruption of the blood-brain barrier and direct neurotoxic effect of contrast agent are the most likely causes". Terlecki M, et al. Transient cortical blindness after coronary artery angiography. Postepy w Kardiologii Interwencyjnej 9: 105-108, No. 1, 2013. Available from: URL: http://dx.doi.org/10.5114/pwki.2013.34036 - Poland 803086999 1 Reactions 18 May 2013 No. 1452 0114-9954/10/1452-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
Transcript of Iopromide
Reactions 1452 - 18 May 2013
SIopromide
Transient cortical blindness: case reportA 32-year-old man developed transient cortical blindness
after receiving iopromide [Ultravist] as a contrast agent forcoronary angiography.
The man was suspected to have Brugada syndrome, andunderwent coronary angiography conducted through thefemoral artery with about 100mL of iopromide used ascontrast agent [route and time to reaction onset not stated].During the procedure, he reported visual impairment with noother focal symptoms. He completely lost his vision within15 minutes. He remained haemodynamically stable, and wasconscious with good verbal contact for the remainder of thecoronary angiography.
Immediately after the procedure, the man underwentophthalmological and neurological consultation. There wereno abnormalities detected other than binocular blindness. ACT scan of the head did not show any pathology. His visualimpairment completely resolved the first day after thecoronary angioplasty. He was discharged home on the thirdday in a good general condition with no symptoms.
Author comment: "Transient cortical visual impairment isa rare, rapidly progressing complication of angiography.Although the exact mechanism of cortical visual impairmentis unknown, the interruption of the blood-brain barrier anddirect neurotoxic effect of contrast agent are the most likelycauses".Terlecki M, et al. Transient cortical blindness after coronary artery angiography.Postepy w Kardiologii Interwencyjnej 9: 105-108, No. 1, 2013. Available from:URL: http://dx.doi.org/10.5114/pwki.2013.34036 - Poland 803086999
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Reactions 18 May 2013 No. 14520114-9954/10/1452-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved
