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    I. INTRODUCTION

    Schizophrenia is a chronic, severe, and disabling mental illness. The termschizophrenia is Greek in origin, and in the Greek meant "split mind." This is not anaccurate medical term. People suffering from schizophrenia may have the followingsymptoms: Delusions which are false personal beliefs held with conviction in spite of

    reason or evidence to the contrary, not explained by that person's culturalcontext. Hallucinations which are perceptions (can be sound, sight, touch, smell, ortaste) that occur in the absence of an actual external stimulus. Also, disorganizedthoughts and behaviors, disorganized speech and catatonic behavior, in which theaffected person's body may be rigid and the person may be unresponsive.

    II. SUMMARY OF THE CASE

    The patient, a 47 year old mother of two, was brought to the mental healthcenter by her sister who expressed concern about recent behavioral changesexhibited by the patient. She stated that the patient was diagnosed withSchizophrenia, undifferentiated type, at age 40 and was placed on Risperdal 1.5 mg

    BID. The patient lived with her sister and was able to perform ADLs independently,until recently, when she discontinued taking her medication.

    As a result of medication noncompliance, the patient became overlyconcerned about insects and bugs that she believed were in her room. She began towear gloves to protect her hands as she sprayed insect repellant on all thefurniture. She also turned the water on in her bathroom sink, believing the bugscontaminated the sink.

    Unfortunately, she neglected to turn the water off and flooded the bathroom.Although she was oriented to TPP, The patients speech had become incoherent attimes. The patient stated that she felt better while taking the medication and,therefore, believed that she was cured of her illness. Consequently, she stoppedtaking the medication. When her sister confronted her about her recent behavioral

    changes, the patient was insightful enough to admit needing help and agreed to seethe nurse at the center where she received follow-up care.

    III. CLARIFY UNKNOWN TERMINOLOGY

    All terminologies are known.

    IV. LEARNING ISSUES AND FORMULATE HYPOTHESIS

    LEARNINGISSUES

    HYPOTHESIS INFERENCES CONCLUSION

    1. What is theeffective dosefor Risperdal?

    Since thepatient can stillperform ADLswe assume thatthe Risperdal1.5mg BIDordered is justwithin the

    In Schizophrenia, Adults withthe medication Risperdalmay be given once or twicedaily.Patients should start with2 mg/day Risperdal. Thedosage may be increased onthe second day to 4 mg/day.

    Rejected.

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    http://www.emedicinehealth.com/script/main/art.asp?articlekey=11106http://www.emedicinehealth.com/script/main/art.asp?articlekey=11106
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    effectivetherapeuticdosage torelieve signsand symptomsof

    Schizophrenia.

    From then on, the dosagecan be maintainedunchanged, or furtherindividualized, if needed.Most patients will benefitfrom daily doses of between

    4 mg/day and 8 mg/day.Doses above 6 mg/day whenadministered twice dailywere associated with moreextra pyramidal symptomsand other adverse effectsand are not generallyrecommended.

    Reference:www.emedicinehealth.com(01/22/12, 1324H)

    Dosage for oral Risperdal Schizophrenia, for adults 2mg/day is the starting dose.Dosage may be increased onthe second day to 4 mg. Mostpatients will benefit fromdaily doses of 4-6 mg. But forElderly with renal or liverdisease: starting dose is 0.5mg twice daily and titrates up

    to 1-2 mg twice a day inincrements of 0.5 mg/day.

    Reference: PPDs NursingDrug Guide 2007, page 421

    2. What route

    was used in

    the order for

    the patient of

    Risperdal 1.5

    mg BID?

    Orally, because

    in the order it is

    given twice a

    day not like for

    intramuscular

    and intravenous

    route that singledosing is

    commonly used.

    Speculative Speculative

    3. What route

    is available

    when taking

    Risperdal?

    Risperdal can

    be given in oral

    tablets form,

    intramuscular

    Risperdal (Risperidone)comes as a tablet, a solution(liquid), and an orallydisintegrating tablet (tabletthat dissolves quickly in the

    Rejected.

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    injection and

    intravenous

    injection but

    should be taken

    with precaution

    for the fasterthe absorption

    the greater risk

    for adverse

    effects.

    mouth) to take by mouth.

    Reference:www.medlineplus.com(01/22/12, 1116H)

    Risperdal can be givenby intramuscular injectioninto the buttock by ahealthcare professional onceevery two weeks. Injectionsshould alternate between thetwo buttocks and is not givenby injection into a vein(intravenously). Injectedrisperidone may take up tothree weeks to beginworking. During this time,oral form of this drug oranother medication for yourcondition by mouth should betaken.

    Reference:www.medlineplus.com(01/22/12, 1209H)

    Health Day Newsabout Risperdal, oral

    antipsychotics appear to bemore effective than Risperdal(risperidone) injections. Thisinjection does not appear toimprove outcomes in patientswith Schizophrenia orSchizoaffective disorder, andis mostly associated withmore injection site woundand extra pyramidal adverseeffects.

    Reference:www.mentalhelp.net(01/22/12, 1234H)

    4. Why werethere no

    reports of thepatients white

    blood cell

    Risperdal isAtypicalantipsychoticwhichcommonly have

    Speculative Speculative

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    countreported?

    adverse effectofAgranulocytosistherefore thereis theimmediate need

    for WBC countmonitoringbefore patientcan get anotherdose. WBCcount required>3500/mm3should bemonthsmonitoredevery 1 weekfor 6.

    5. Does whiteblood cell

    countmonitoring

    alwaysnecessary for

    patients takingRisperdal?

    Yes, Risperdal isstill a Atypicalantipsychoticwhich has aadverse effectofAgranulocytosis,even thoughlesser thanClozapine andOlanzapine stillit has this effectthat is why it isadvised to betaken atbedtime.

    Leukopenia, Neutropenia,and Agranulocytosis havebeen reported as adverseeffects of antipsychotics,including Risperdal. Patientswith history of a clinicallysignificant low white bloodcell count (WBC) or a drug-inducedleukopenia/neutropeniashould have their completeblood cell count (CBC)monitored frequently duringthe first few months oftherapy and discontinuationof Risperdal should beconsidered at the first sign ofa clinically significant declinein WBC in the absence ofother causative factors.Reference:www.dailymed.com(01/22/12, 1344H)

    Accepted.

    6. Does thepatient gainedweight during

    hermedicationregimen?

    One side effectof anti

    psychotics isweight gain.

    Speculative Speculative

    7. What areother physical

    All generation ofAntipsychotics

    Some adverse effects(occurring in 1 to 13 percent

    Accepted.

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    patientbelieving thatinsects andbugs areinvading herroom and

    wearinggloves. Is thisan effect ofthe abruptwithdrawalfrom hermedicationRisperdal?

    experiencesdelusions aboutinsects andbugs infecting/invading herroom. And

    abruptdiscontinue ofmedicationcauses reboundeffect of muchmore intensesigns andsymptoms.

    Schizophrenia signs andsymptoms (hallucinationsand delusions) may bepresent as an effect ofwithdrawal.Reference: www.about.com

    (01/23/12, 1359H)

    11. Is therereally a needforPsychotherapy plusantipsychotics to effectivelymanage thesymptoms ormedicationsalone woulddo?

    The treatmentof choice forSchizophrenia isPsychotherapyplus the antipsychoticmedicationregimen thatshould bescheduled andplanned hand inhand for themaximumbenefit for thepatient.

    Speculative Speculative

    12. What isthe treatmentof choice forthe patientsdisorder?

    The treatmentof Choice forSchizophrenia isthe combinationofPsychotherapyand antipsychoticmedication.

    Currently, there is no

    method for preventing

    schizophrenia and there is no

    cure. A comprehensive

    treatment program can be

    used and this includes:

    Antipsychotic medication,

    Education & support, for both

    ill individuals and families,

    Social skills training,

    Rehabilitation to improve

    activities of daily living,

    Vocational and recreationalsupport and Cognitive

    therapy.

    Reference:

    www.nursingcrib.com

    (01/23/12, 1543H)

    Rejected.

    13. DoesSchizophrenia

    It is brought bythe non-

    Undifferentiatedschizophrenia symptoms may

    Rejected.

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    disordermanifestspeech

    problems orwas thepatients

    incoherentspeech wasonly brought

    by thewithdrawal?

    compliancebecause in themanifestations

    ofSchizophrenia itdoes not involve

    speechproblems.

    include symptoms of morethan one other type of

    schizophrenia. Muscle rigidityis common among the signsand symptoms which may

    include the face and the jaw.

    Reference:www.nursingcrib.com(01/23/12, 1842H)

    V. NURSING CARE PLANS

    ASSESSMENT

    NURSINGDIAGNOSI

    S

    PLANNING NURSINGINTERVENTION

    S

    RATIONALE EXPECTEDOUTCOMES

    Objective:

    Patient hasincoherent

    speech

    Impairedverbal

    communication

    related toside

    effects ofmedicatio

    n asmanifeste

    d bypatientsincoherent speech

    After 24hours ofnursing

    interventions the

    patient willexpress atleast two

    from theseneeds

    a. need forher

    medicationb. need ofhelp forbathing

    c. need forfood

    d. need ofhelp fortoiletinge. needsupport

    from familymembers

    andcaregiverthrough

    congruentverbal and

    non verbal

    1. Determineability to read/write.

    2. Establishrelationshipwith the client,listeningcarefully andattending topatientsverbal/nonverbalexpressions.

    3. Maintain eyecontact,preferably atpatients level.

    4. Keepcommunicationsimple, usingall modes.

    5. Maintain acalm, unhurriedmanner.Providesufficient time

    1. Toevaluatemusculoskeletaldexterity.

    2. To assistclient inexpressingneeds,wants.

    3. Toestablish ameans ofcommunication

    4. To helpaccessinformation:visual,auditory,andkinesthetic.

    5.Individuals

    After 24hours ofnursing

    interventions the

    patient wasable to

    express herneeds as

    evidencedby the

    following:a. Poin

    ting to thetelephoneto call her

    sister.b. Writing on theboard thatshe needsto go to

    thebathroom.

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    communication.

    for client torespond.

    6. Use andassist patientto learntherapeuticcommunication.

    7. Providerealityorientation byrespondingwith simplestraightforward, honeststatements.

    8. Validatemeaning ofnonverbalcommunication; do not makeassumptions.Be honest; if itis notunderstood askassistance fromothers.

    9. Consider useof alternativemethods ofcommunicationsuch as pictureboard, handsignalsincorporatinginformationabout type ofdisability

    withexpressiveaphasiamay talkmore easilywhen they

    are restedand relaxedand whenthey aretalking toone personat a time.

    6. Improvesgeneralcommunication skills.

    7. Tomaintaincontact withreality.

    8.Assumptions may bewrong.

    9. Cuesnon- verbalor verbalcan be usedto attendpatientsneeds.

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    present.

    10. Involvefamily in planof care asmuch as

    possible.

    10.Enhancesparticipation

    andcommitment to plan.

    ASSESSMENT

    NURSINGDIAGNOSI

    S

    PLANNING NURSINGINTERVENTION

    S

    RATIONALE EXPECTEDOUTCOMES

    Subjective:

    Patientsfixed falsebelief of

    insects andbugs

    invading herroom.

    Objective:

    Patientspraying

    insectrepellants in

    her room.

    Disturbedthoughtcontent

    related topsycholog

    icalconflicts

    asmanifeste

    d bypatientsexperienc

    es ofdelusions.

    After 24hours ofnursing

    interventions the

    patient willbe able tointeract on

    reality-based

    topics byengagingself to atleast 2 of

    thefollowingactivities:

    a. Mindpuzzles

    b. Physical exercisec. Boardgamesd. Arts

    andCrafts

    making

    1. Be sincereand honestwhencommunicatingwith the client.Avoid vague orevasiveremarks.

    2. Beconsistent insettingexpectations,enforcing rulesand so forth.

    3. Encourage

    the client totalk, but do notpry forinformation.

    1.Delusionalclient areextremelysensitiveaboutothers andcanrecognizesincerity.Evasivecommentsor hesitationreinforcesmistrust ordelusions.

    2. Clear,consistentlimitsprovide asecurestructure forthe client.

    3. Probing

    increasesthe clientssuspicionandinterfereswith thetherapeuticrelationship.

    After 24hours ofnursing

    interventions the

    patient wasable to

    interact onrealitybased

    topics byengagingherself to

    thefollowing:

    a. Patientattendingphysicalexercise

    with otherpatients.b. Patientansweringcrossword

    puzzlebook.

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    4. Destructpatient fromdelusions bygiving physicaland intellectualchallengingactivities suchas board gamesand exercises.

    5. Initially, donot argue with

    the client or tryto convince theclient that thedelusions arefalse or unreal.

    6. Interact withthe client on

    the basis ofreal things; donot dwell onthe delusionalmaterials.

    7. Do not bejudgmental orbelittle or jokeabout theclients beliefs.

    8. Never

    4. Engagingpatient tootheractivitiesprovides thepatient toignoredelusionsand focusmore in thereality.

    5. Logical

    argumentdoes notdispeldelusionalideas andcaninterferewith thedevelopment of trust.

    6.

    Interactingabout realityis healthyfor theclient.

    7. Theclients

    delusionsand feelingsare notfunny to himor her. Theclient maynotunderstandor may feel

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    convey to theclient that youaccept thedelusional asreality.

    rejected byattempts athumor.

    8. Indicatingbelief in the

    delusionsreinforcesthe clientsillness.

    ASSESSMENT

    NURSINGDIAGNOSI

    S

    PLANNING NURSINGINTERVENTION

    S

    RATIONALE EXPECTEDOUTCOMES

    Subjective:

    Patientssister

    report ofpatient

    discontinuing her

    medication.

    Patientsfixed falsebelief of

    insects andbugs

    invadingher room.

    Objective:

    Patientspraying

    insectrepellants

    in her

    room.

    Patient hasincoherent

    speech.

    Non

    compliance relatedto alteredthoughtcontent

    asmanifeste

    d bypatientsmanifestsexacerbat

    ion of

    symptoms such asincoherent speech

    anddelusions.

    After 24

    hours ofnursing

    interventionsthe patient

    will verbalizeat least one

    from thefollowing

    understanding:

    a. aboutaccurate

    knowledge ofconditionb. about

    medication/treatmentregimen.

    1. Note length

    of illness.

    2. Developtherapeuticnurse- clientrelationship.

    3. Reviewtreatmentstrategies andidentify whichamonginterventions

    aretherapeuticallymet and areleastamenable tocompliance.

    4. Give

    1. Patients

    tend tobecomepassiveanddependentin longterm,debilitatingillnesses.

    2.Promotes

    trust,providesatmosphere in whichpatient canfreelyexpressconcerns.

    3. Setsprioritiesand

    encouragesproblemsolvingareas ofconflict.

    After 24

    hours ofnursing

    interventions the

    patient wasable to

    express herneeds as

    evidencedby the

    following:c. Poin

    ting to thetelephoneto call her

    sister.d. Writing on theboard thatshe needsto go to

    thebathroom.

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    informationabout illness,treatment andmedications inmanageableamounts,

    using verbal orwritten, atlevel ofpatientsability.

    5. Havepatientparaphraseinstructions/informationheard.

    6. Acceptpatientschoice of pointand avoidconfrontation.

    7. Contractwith thepatient forparticipation incare.

    8. Encouragepatient tomaintain self care in and outof hospitalcare andacceptpatientsevaluation ofown strengthandweaknesses.

    9. Provideinformationand helppatient to

    4.Facilitateslearning.

    5. Helpsvalidatepatientsunderstand

    ing andrevealsmisconceptions.

    6. Tomaintainopencommunication.

    7.Enhancescommitment to followthrough.

    8. Toimprovepatientsabilities.

    9.Promotesindependence andencourages

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    know whereand how tofind it on own.

    10. Stress

    importance ofthe patientsknowledgeandunderstandingof the need fortreatment/medication.

    11. Develop asystem for selfmonitoring.

    informeddecisionmaking.

    10.Enhances

    participation andcommitment to plan.

    11. Toprovidepatientwith self

    control andassist withmakingchoices.

    VI. DRUG STUDY

    GENERIC

    (Brand)

    DOSAGE INDICATION ADVERSE

    EFFECT

    NURSING

    CONSIDERATIONRisperidone

    (Risperdal)

    1.5 mg BID

    Oral:

    Schizophrenia Adult:

    start with 2

    mg. dosage

    may

    increased

    2nd day to 4

    mg. Most

    patient will

    benefit from

    daily dosesof 4-6 mg.

    Reference:

    PPDs

    Nursing Drug

    Guide 2007,

    page 421

    Acute and

    chronic

    psychoses

    include firstepisode

    psychoses and

    other psychotic

    conditions in

    which positive

    and/ or negative

    symptoms are

    prominent. Also

    alleviates

    symptomsassociated with

    schizophrenia.

    Treatment of

    behavioral

    disturbances in

    patient with

    dementia whom

    -Insomnia,

    agitation,

    anxiety, head

    ache, fatigue,dizziness,

    impaired

    concentration,

    constipation,

    nausea, and

    vomiting,

    blurred vision.

    1. Assess

    potential for

    interactions with

    otherprescriptions,

    OTC

    medications, or

    herbal products

    patient may be

    taking.

    2. Monitor vital

    signs; fasting

    lipid profile andfasting blood

    glucose/Hgb Alc

    (prior to

    treatment, at 3

    months, then

    annually); body

    mass index BMI,

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    symptoms e.g.,

    aggressiveness,

    activity

    disturbances or

    psychotic

    symptoms areprominent.

    personal /family

    history of

    obesity, waist

    circumference.

    3. Weight shouldassess prior to

    treatment.

    4. Be alert to

    the potential

    orthostatic

    hypotension.

    Reference: PPDs Nursing Drug Guide 2007, page 421

    VII. POSSIBLE OUTCOMES

    Outcome A (Best Case Scenario)

    The patient following the following management gain insight and control of

    signs and symptoms from her Undifferentiated Schizophrenia condition:

    Patients should be educated about the following:

    o Social skills training

    o Medication compliance

    o Reducing expressed emotions

    o Cognitive rehabilitation

    o Family therapy

    Family education should involve reduction of expressed emotions, criticism,hostility, or overprotection of the patient; such reduction may lead to decreases inrelapse rates.

    Reference: www.nursingcrib.com (01/23/12, 1956H)

    Outcome B (Worst Case Scenario)

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    The patient noncompliant with her medication regimen experiences

    worsening of signs and symptoms.

    Patient ignoring about the following:

    o Social skills training = poor relationship, loss of ego boundaries, which

    poses difficulties for themselves and others in their environment andcommunity.

    o Medication compliance = abrupt discontinuation of medication causes

    abrupt and intense signs of symptoms of delusions, hallucinations,agitation.

    o Cognitive rehabilitation = Patients experiencing delusions and

    hallucinations are at greater risk of imposing harm to others. Thepatient needs to be institutionalized.

    Reference: www.nursingcrib.com (01/23/12, 1956H)

    VIII. CONCEPT MAP

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    Diagram 1. Concept Map for the patients Undifferentiated Schizophrenia

    case

    REFERENCES

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    Published References

    Kasper et al. 2005 Harrisons Principle of Internal Medicine Manual of MedicineInternational Edition 16th Edition

    PPDs Nursing Drug Guide 2007, page 421

    Videbeck S. L 2008 Psychiatric Mental Health Nursing Fourth EditionChina, Lippincott Williams and Wilkins Chapter 14 pages 267 290

    Online References

    RisperdalOnline article retrieved from www.emedicine.medscape.com (01/22/2012, 2034H)

    Risperdal

    Online article retrieved from www.medlineplus.com (01/22/2012, 2209H)

    SchizophreniaOnline article retrieved from www.emedicine.medscape.com (01/22/2012, 1817H)

    SchizophreniaOnline article retrieved from www.medicinenet.com (01/30/2012, 1515H)

    Undifferentiated schizophreniaOnline article retrieved from www. Freemedical-dictionary.com (01/30/2012, 1442H)

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