INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la...

30
Máster y Experto en suplementación nutricional integrativa basado en la evidencia 1 Máster y Experto en suplementación nutricional integrativa basado en la evidencia INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD INTEGRATIVA AYLA FAULÍN GARCÍA DEPARTAMENTO ENFERMERÍA CMI EXPERTA EN YOGA Y MEDITACIÓN

Transcript of INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la...

Page 1: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 1

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia

INTEGRACIOacuteN DE LAS TEacuteCNICAS MENTE-CUERPO EN SALUD INTEGRATIVA

AYLA FAULIacuteN GARCIacuteADEPARTAMENTO ENFERMERIacuteA CMIEXPERTA EN YOGA Y MEDITACIOacuteN

ESTREacuteS

REACCIONES BIOLOacuteGICAS

REACCIONES PSICOLOacuteGICAS

REACCIONES CONDUCTUALES

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 3

TEacuteCNICAS MENTE-CUERPO

ldquointervenciones que usan una variedad de teacutecnicas disentildeadas para facilitar la capacidad de la mente para influir sobre las funciones corporales y sus siacutentomasrdquo

Instituto Nacional de la Salud en USA

LA MEDITACIOacuteN TIENE LA CAPACIDAD DE ESTIMULAR NUESTRO CEREBRO PARA

LIBERAR HORMONAS Y NEUROTRANSMISORES

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 2: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

ESTREacuteS

REACCIONES BIOLOacuteGICAS

REACCIONES PSICOLOacuteGICAS

REACCIONES CONDUCTUALES

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 3

TEacuteCNICAS MENTE-CUERPO

ldquointervenciones que usan una variedad de teacutecnicas disentildeadas para facilitar la capacidad de la mente para influir sobre las funciones corporales y sus siacutentomasrdquo

Instituto Nacional de la Salud en USA

LA MEDITACIOacuteN TIENE LA CAPACIDAD DE ESTIMULAR NUESTRO CEREBRO PARA

LIBERAR HORMONAS Y NEUROTRANSMISORES

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 3: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 3

TEacuteCNICAS MENTE-CUERPO

ldquointervenciones que usan una variedad de teacutecnicas disentildeadas para facilitar la capacidad de la mente para influir sobre las funciones corporales y sus siacutentomasrdquo

Instituto Nacional de la Salud en USA

LA MEDITACIOacuteN TIENE LA CAPACIDAD DE ESTIMULAR NUESTRO CEREBRO PARA

LIBERAR HORMONAS Y NEUROTRANSMISORES

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 4: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

TEacuteCNICAS MENTE-CUERPO

ldquointervenciones que usan una variedad de teacutecnicas disentildeadas para facilitar la capacidad de la mente para influir sobre las funciones corporales y sus siacutentomasrdquo

Instituto Nacional de la Salud en USA

LA MEDITACIOacuteN TIENE LA CAPACIDAD DE ESTIMULAR NUESTRO CEREBRO PARA

LIBERAR HORMONAS Y NEUROTRANSMISORES

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 5: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

LA MEDITACIOacuteN TIENE LA CAPACIDAD DE ESTIMULAR NUESTRO CEREBRO PARA

LIBERAR HORMONAS Y NEUROTRANSMISORES

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 6: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull LA DOPAMINA juega un papel clave en la capacidad del cerebro para experimentar placer sentirse recompensado y mantener la atencioacuten

bull LA SEROTONINA tiene un efecto calmante

Alivia la tensioacuten y nos ayuda a sentir menos estreacutes y estar maacutes concentrado Los bajos niveles de este neurotransmisor se han vinculado a las migrantildeas la ansiedad el trastorno bipolar la apatiacutea los sentimientos de inutilidad la fatiga y el insomnio

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 7: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull LA OXITOCINA la misma sustancia quiacutemica cuyos niveles aumentan durante la excitacioacuten sexual el parto y la lactancia es una hormona del placer Crea sentimientos de calma satisfaccioacuten y seguridad al tiempo que reduce el miedo y la ansiedad

bull LAS ENDORFINAS Estos neurotransmisores desempentildean muchas funciones relacionadas con el bienestar incluyendo la disminucioacuten de la sensacioacuten de dolor y la reduccioacuten de los efectos secundarios del estreacutes

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 8: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

BENEFICIOS DE LA MEDITACIOacuteN

bull MITIGAR LOS EFECTOS SECUNDARIOS DE LOS TRATAMIENTOS

bull NOTORIA REDUCCIOacuteN DEL ESTREacuteS

bull REGULA SISTEMA INMUNOLOacuteGICO

bull CLARIDAD MENTAL Y MENTE POSITIVA

bull MEJORA LA RESISTENCIA A LAS ENFERMEDADES

bull REDUCE EL RIESGO DE MUCHAS PATOLOGIacuteAS

bull AUMENTA LA ENERGIacuteA VITAL

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 9: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull DISMINUCIOacuteN DE ESTADO ANSIOSO-DEPRESIVO

bull DISMINUYE LA PERCEPCIOacuteN DEL DOLOR

bull MEJORA LA CALIDAD DEL SUENtildeO

bull EL LOGRO DE TUS METAS SE HACE MAacuteS FAacuteCIL

bull MAYOR FACILIDAD DE VIVIR EN TIEMPO PRESENTE

bull DESARROLLO DE UNA FORTALEZA INTERIOR

bull hellip

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 10: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

EMOCIONES PENSAMIENTOS

RESPUESTAS FISIOLOacuteGICAS

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 11: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

TEacuteCNICAS

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 12: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull YOGA Y RELAJACIOacuteN

bull MEDITACIOacuteN

bull MINDFULNESS

bull VISUALIZACIOacuteN O IMAGINERIacuteA GUIADA

bull TERAPIAS COGNITIVO CONDUCTUALES

bull HIPNOSIS

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 13: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull LA ORACIOacuteN

bull TERAPIAS MANUALES

bull TAI CHI CHUAN

bull ZEN

bull MEDITACIOacuteN TRASCENDENTAL

hellip

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 14: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

COHERENCIA CARDIACA

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 14

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 15: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

CUATRO PASOS ANTIESTRES bull TRANQUILIZAR EL CORAZON

RESPIRACIOacuteN TORAacuteCICA

bull TRANQUILIZAR LA MENTE VISUALIZACIOacuteN CREATIVA

bull TRASLADAR LA IMAGEN AL CORAZOacuteN

bull TRASLADAR LA EMOCIOacuteN AL RESTO DEL CUERPO

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 15

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 16: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

CASOS CLIacuteNICOS

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 17: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

MANUELA 45 antildeos Insomnio croacutenico Ama de casa

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 18: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

LOURDES paciente 50 antildeos Diag fibromialgia Administrativa

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 19: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

ESTUDIOS CIENTIacuteFICOS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 19

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 20: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Ocho semanas de meditacioacuten pueden cambiar el cerebroLas aacutereas de materia gris relacionadas con la memoria la empatiacutea y el estreacutes se

transforman de forma considerable

La meditacioacuten puede provocar cambios considerables en las estructuras del cerebro

bull No lo dice un grupo laquonew ageraquo ni unos amantes de la pseudociencia o de la falsa espiritualidad sino un equipo de psiquiatras liderado por el Hospital General de Massachusetts que ha realizado el primer estudio que documenta coacutemo ejercitar la meditacioacuten puede afectar al cerebro Seguacuten sus conclusiones publicadas en Psychiatry Research la praacutectica de un programa de meditacioacuten durante ocho semanas puede provocar considerables cambios en las regiones cerebrales relacionadas con la memoria la autoconciencia la empatiacutea y el estreacutes Es decir que algo considerado espiritual nos transforma fiacutesicamente y puede mejorar nuestro bienestar y nuestra salud

bull laquoAunque la praacutectica de la meditacioacuten estaacute asociada a una sensacioacuten de tranquilidad y relajacioacuten fiacutesica los meacutedicos han afirmadodurante mucho tiempo que la meditacioacuten tambieacuten proporciona beneficios cognitivos y psicoloacutegicos que persisten durante todo el diacutearaquo explica la psiquiatra Sara Lazar autora principal del estudio laquoLa nueva investigacioacuten demuestra que los cambios en la estructura del cerebro pueden estar detraacutes de esos beneficios demostrados y que la gente no se siente mejor solo porque se han relajadoraquo apunta

CLIacuteNICA MEDICINA INTEGRATIVA

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 21: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

LA MEDITACIOacuteN NOS AYUDA A SER MAacuteS POSITIVOS PREVENIR LA ANSIEDAD O ENFERMEDADES Y TRASTORNOS COMO EL ALZHEIMER EL CAacuteNCER O LA

ESQUIZOFRENIAUn grupo de investigadores de la Universidad de Yale ha comprobado los beneficios que tiene la meditacioacuten sobre el cerebro

El estudio demuestra que la praacutectica de la meditacioacuten permite alejar con maacutes frecuencia los pensamientos negativos y desconectaraquellas aacutereas cerebrales en las que se desarrollan patologiacuteas como el autismo y la esquizofrenia

La investigacioacuten publicada en Proceedings de la Academia Nacional de Ciencias de EEUU ha consistido en la realizacioacuten de resonancias magneacuteticas a personas que practican frecuentemente la meditacioacuten y a otras que no la habiacutean realizado nunca mientras practicaban tres teacutecnicas de diferentes

Descubrieron que las personas acostumbradas a meditar mostraban una disminucioacuten de la actividad en las aacutereas del cerebro implicadas en los despistes y trastornos como el deacuteficit de atencioacuten ansiedad y el trastorno de hiperactividad e incluso la acumulacioacuten de placas beta-amiloide en la enfermedad de Alzheimer

Judson A Brewer responsable de la investigacioacuten afirma que ldquose ha demostrado que la meditacioacuten ayuda en una variedad de problemas de salud como dejar de fumar lidiar con el caacutencer e incluso prevenir la psoriasishellip Muchas formas de enfermedad mental se caracterizan por la preocupacioacuten por los propios pensamientos una condicioacuten que la meditacioacuten parece afectarrdquo

El investigador tambieacuten afirmoacute que las personas que recurren habitualmente a la meditacioacuten tienen una concepcioacuten diferente sobre el mundo permaneciendo en constante alerta frente a lo exterior en lugar de escuchar con tanto detenimiento el ldquoyo interiorrdquo en los pensamientos o las divagaciones En las formas patoloacutegicas estos estados estaacuten asociados con enfermedades como el autismo y la esquizofrenia

CLIacuteNICA MEDICINA INTEGRATIVA

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 22: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

UN ESTUDIO CIENTIacuteFICO DEMUESTRA QUE LAS PERSONAS QUE PRACTICAN MEDITACIOacuteN GOZAN DE MEJOR SALUD Y BIENESTAR

Los doctores Nicolaacutes Fayed jefe de servicio de diagnoacutestico por imagen de Hospital Quiroacuten

Zaragoza Yolanda Loacutepez del Hoyo del departamento de sociologiacutea y psicologiacutea de la Universidad

de Zaragoza y Javier Garciacutea-Campayo del servicio de psiquiatriacutea del Hospital Miguel Servet de

Zaragoza han realizado un nuevo estudio que demuestra que las personas que practican

meditacioacuten gozan de mejor salud y bienestar

Este estudio que fue publicado el pasado mes de marzo en la prestigiosa revista cientiacutefica PLOS

ONE ha sido realizado con teacutecnicas de resonancia magneacutetica que permiten medir las sustancias

quiacutemicas e interconexiones neuronales y por lo tanto los cambios cerebrales que se producen en

meditadores zen Para ello el Dr Nicolaacutes Fayed y sus colegas compararon los cerebros de diez

meditadores de un monasterio budista quienes contaban con una media de 191 meses y por lo

menos una hora diaria de meditacioacuten y otras diez personas sanas que no practicaban meditacioacuten

pertenecientes al equipo del Hospital Miguel Servet de Zaragoza

ldquoTal y como muestran este y otros estudios de investigacioacuten hay una clara relacioacuten entre nuestras

neuronas y las emocionesrdquo Ademaacutes sentildeala el Dr Nicolaacutes Fayed ldquoel Dr Murakami en su estudio

The estructure of mindful brain ya demostroacute con resonancia funcional coacutemo los meditadores

presentan un aumento de la actividad en el loacutebulo frontal (asociado a las emociones de felicidad y

bienestar) y tambieacuten de la iacutensula que funciona como el centro neuroloacutegico de la integracioacuten

afectiva autoacutenoma y cognitivardquo Por otro lado el jefe de servicio de diagnoacutestico por imagen de

Hospital Quiroacuten Zaragoza explica que ldquootros estudios en pacientes con estreacutes han demostrado

cambios cerebrales en tan soacutelo ocho semanas despueacutes de comenzar la meditacioacutenrdquo

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 23: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

AmritaMeditation Technique onAdrenaline and Cortisol Levels in Healthy

VolunteersBalakrishnan Vandana1 Kannan Vaidyanathan2 Lakshmiy Ammal Saraswathy1

Karimassery Ramaiyer Sundaram3 and Harish Kumar4

1Department of Physiology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

2Department of Biochemistry Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

3Department of Biostatistics Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

4Department of Endocrinology Amrita Institute of Medical Sciences Amrita Lane Ponekkara PO Cochin 682 041 Kerala India

Correspondence should be addressed to Balakrishnan Vandana vandanabalakrishnanaimsamritaedu

Received 9 September 2010 Revised 27 November 2010 Accepted 8 January 2011

Copyright copy 2011 Balakrishnan Vandana et al This is an open access article distributed under the Creative Commons Attribution

License which permits unrestricted use distribution and reproduction in any medium provided the original work is properly

cited

Conclusion

The significant fall in adrenaline levels and the downward trend seen in cortisol show the immediate and longterm efficacy of the IAM Technique in reducing the stress

hormones

CLIacuteNICA MEDICINA INTEGRATIVA

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 24: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

J Health Psychol 2018 May 11359105318772608 doi 1011771359105318772608 [Epub ahead of print]

Mediational pathways of meditation and exercise on mental health and perceived stress A randomized controlled trialGoldstein E1 Topitzes J2 Brown RL1 Barrett B1

Author information

Abstract

This study investigated the effects of mindfulness and exercise training on indicators of mental health and stress by examining shared mediators of program effects Community-recruited adults ( Nthinsp=thinsp413) were randomized into one of three conditions (a) mindfulness-based stress reduction (b) moderate intensity exercise or (c) wait-list control Composite indicator structural equation models estimated direct indirect and total effects Results showed that mindfulness-based self-efficacy fulfilled a prominent role in mediating meditation and exercise program effects Findings suggest that mindfulness and exercise training share similar mechanisms that can improve global mental health including adaptive responses to stress

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 24

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 25: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Enhancement of Meditation Analgesia by Opioid Antagonist in ExperiencedMeditators

May LM1 Kosek P2 Zeidan F3 Berkman ET4

Author information

Abstract

OBJECTIVE

Studies have consistently shown that long-term meditation practice is associated with reduced pain but the neural mechanisms by which long-term meditation practice reduces pain remain unclear This study tested endogenous opioid involvement in meditationanalgesia associatedwith long-term meditation practice

METHODS

Electrical pain was induced with randomized double-blind cross-over administration of the opioid antagonist Naloxone (015mgkg bolusdose then 02mgkghr infusion dose) with 32 healthy experienced meditation practitioners and a standardized open monitoring meditation

RESULTS

Under saline pain ratings were significantly lower during meditation (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) than at baseline (pain intensity 686 plusmn104 t(31) = 2476 p = 0019 Cohens d = 046 pain unpleasantness 496 plusmn175 t(31) = 3746 p = 0001 Cohens d = 068) confirming the presence of meditation analgesia Comparing saline and Naloxone revealed significantly lower pain intensity(t(31) = 312 p = 0004 d = 056) and pain unpleasantness (t(31) = 347 p = 0002 d = 062) during meditation under Naloxone (painintensity 553 plusmn 154 pain unpleasantness 295 plusmn 188) than under saline (pain intensity 641 plusmn 132 pain unpleasantness 398 plusmn 217) Naloxone not only failed to eliminate meditation analgesia it made meditation analgesia stronger

CONCLUSIONS

Long-term meditation practice does not rely on endogenous opioids to reduce pain Naloxones blockade of opioid receptorsenhanced meditation analgesia pain ratings during meditation were significantly lower under Naloxone than under saline Possible biologicalmechanisms by which Naloxone-induced opioid receptor blockade enhances meditation analgesia are discussed

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 25

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 26: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Alterations in Brain and Immune Function Produced by Mindfulness Meditation

Davidson Richard J PhD Kabat-Zinn Jon PhD Schumacher Jessica MS Rosenkranz Melissa BA Muller Daniel MD PhD Santorelli Saki F EdD Urbanowski Ferris MA Harrington Anne PhD Bonus Katherine MA Sheridan John F PhD

Psychosomatic Medicine July 2003 - Volume 65 - Issue 4 - p 564ndash570

doi 10109701PSY000007750567574E3

Article

Abstract

Author Information

Objective The underlying changes in biological processes that are associated with reported changes in mental and physical health in response to meditation have not been systematically explored We performed a randomized controlled study on the effects on brain and immune function of a well-known and widely used 8-week clinical training program in mindfulness meditation applied in a work environment with healthy employees

Methods We measured brain electrical activity before and immediately after and then 4 months after an 8-week training program in mindfulness meditation Twenty-five subjects were tested in the meditation group A wait-list control group (N = 16) was tested at the same points in time as the meditators At the end of the 8-week period subjects in both groups were vaccinated with influenza vaccine

Results We report for the first time significant increases in left-sided anterior activation a pattern previously associated with positive affect in the meditators compared with the nonmeditators We also found significant increases in antibody titers to influenza vaccine among subjects in the meditation compared with those in the wait-list control group Finally the magnitude of increase in left-sided activation predicted the magnitude of antibody titer rise to the vaccine

Conclusions These findings demonstrate that a short program in mindfulness meditation produces demonstrable effects on brain and immune function These findings suggest that meditation may change brain and immune function in positive ways and underscore the need for additional research

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 26

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 27: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

J Neurosci Author manuscript available in PMC 2011 Oct 6

Published in final edited form as

J Neurosci 2011 Apr 6 31(14) 5540ndash5548 doi 101523JNEUROSCI5791-102011

PMCID PMC3090218 NIHMSID NIHMS286473 PMID 21471390

Brain Mechanisms Supporting Modulation of Pain by Mindfulness Meditation

F Zeidan1 KT Martucci1 RA Kraft2 NS Gordon3 JG McHaffie1 and RC Coghill1

bull Mindfulness meditation is characterized by two distinct cognitive practices The fundamental practice of mindfulness is called focused attention (Lutz et al 2008) or Shamatha (Sanskrit translation calm abiding) (Wallace 2006) Focused attention promotes a sense of detachment from ongoing affective states and enhances cognitive control (Maclean et al 2010 Zeidan et al 2010c) Traditionally focused attention is cultivated as a prerequisite to another form of mindfulness meditation labeled open monitoring(Lutz et al 2008)or Vipassana (Sanskrit translation insight into the nature of reality)(Wallace 2006) Open monitoring practitioners commonly refer to mindfulness as a moment-to-moment non-evaluative awareness of ldquowhatever arisesrdquo (Wallace 2006) The present findings therefore are distinct from open monitoringrsquos effects on pain In open monitoring meditators are taught to fully experience the intensity of a sensory event Consistent with this open monitoring has been found to reduce painunpleasantness but not pain intensity ratings (Brown and Jones 2010 Perlman et al 2010) Thus focused attention may attenuate pain by altering the elaboration of nociceptive information to pain whereas open monitoring promotes a non-evaluativestance to a fully experienced sensory event

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 27

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 28: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

REFERENCIAS

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 28

bull Allison PD Missing data Thousand Oaks Calif Sage Publications 2002

bull Baliki MN Geha PY Fields HL Apkarian AV Predicting value of pain and analgesia nucleus accumbens response to noxious stimuli changes in the presenceof chronic pain Neuron 201066149ndash160 [PMC free article] [PubMed]

bull Bantick SJ Wise RG Ploghaus A Clare S Smith SM Tracey I Imaging how attention modulates pain in humans using functional MRI Brain 2002125310ndash319 [PubMed]

bull Berthier M Starkstein S Leiguarda R Asymbolia for pain a sensory-limbic disconnection syndrome Ann Neurol 19882441ndash49 [PubMed]

bull Brown CA Jones AK Meditation experience predicts less negative appraisal of pain Electrophysiological evidence for the involvement of anticipatory neural responses Pain 2010 epub ahead of print [PubMed]

bull Buhle J Wager TD Does meditation training lead to enduring changes in the anticipation and experience of pain Pain 2010 epub ahead of print [PubMed]

bull Bush G Luu P Posner MI Cognitive and emotional influences in anterior cingulate cortex Trends Cogn Sci 20004215ndash222 [PubMed]

bull Buxton RB Wong EC Frank LR Dynamics of blood flow and oxygenation changes during brain activation the balloon model Magn ResonMed 199839855ndash864 [PubMed]

bull Cahn BR Polich J Meditation states and traits EEG ERP and neuroimaging studies Psychol Bull 2006132180ndash211 [PubMed]

bull Coghill RC McHaffie JG Yen YF Neural correlates of interindividual differences in the subjective experience of pain Proc Natl Acad Sci U S A 20031008538ndash8542 [PMC free article] [PubMed]

bull Coghill RC Sang CN Maisog JM Iadarola MJ Pain intensity processing within the human brain a bilateral distributed mechanism J Neurophysiol 1999821934ndash1943 [PubMed]

bull Crick F Function of the thalamic reticular complex the searchlight hypothesis Proc Natl Acad Sci U S A 1984814586ndash4590 [PMC free article] [PubMed]

bull Critchley HD The human cortex responds to an interoceptive challenge Proc Natl Acad Sci U S A 20041016333ndash6334 [PMC free article] [PubMed]

bull Critchley HD Wiens S Rotshtein P Ohman A Dolan RJ Neural systems supporting interoceptive awareness Nat Neurosci 20047189ndash195 [PubMed]

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 29: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

bull Farb NA Segal ZV Mayberg H Bean J McKeon D Fatima Z Anderson AK Attending to the present mindfulness meditation revealsdistinct neural modes of self-reference Soc Cogn Affect Neurosci 20072313ndash322 [PMC free article] [PubMed]

bull Friedman DP Murray EA OrsquoNeill JB Mishkin M Cortical connections of the somatosensory fields of the lateral sulcus of macaques evidence for a corticolimbic pathway for touch J Comp Neurol 1986252323ndash347 [PubMed]

bull Grant JA Rainville P Pain sensitivity and analgesic effects of mindful states in Zen meditators a cross-sectional study PsychosomMed 200971106ndash114 [PubMed]

bull Grant JA Courtemanche J Rainville P A non-elaborative mental stance and decoupling of executive and pain-related corticespredicts low pain sensitivity in Zen meditators Pain 2010 epub ahead of print [PubMed]

bull Grossman P Niemann L Schmidt S Walach H Mindfulness-based stress reduction and health benefits A meta-analysis J Psychosom Res 20045735ndash43 [PubMed]

bull Guillery RW Feig SL Lozsadi DA Paying attention to the thalamic reticular nucleus Trends Neurosci 19982128ndash32 [PubMed]

bull Holzel BK Ott U Hempel H Hackl A Wolf K Stark R Vaitl D Differential engagement of anterior cingulate and adjacent medial frontal cortex in adept meditators and non-meditators Neurosci Lett 200742116ndash21 [PubMed]

bull Kilmer W A thalamo-cortical model of the executive attention system Biol Cybern 200184279ndash289 [PubMed]

bull Koyama T McHaffie JG Laurienti PJ Coghill RC The subjective experience of pain where expectations become reality Proc NatlAcad Sci U S A 200510212950ndash12955 [PMC free article][PubMed]

bull Luh WM Wong EC Bandettini PA Hyde JS QUIPSS II with thin-slice TI1 periodic saturation a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling Magn Reson Med 1999411246ndash1254 [PubMed]

bull Lutz A Slagter HA Dunne JD Davidson RJ Attention regulation and monitoring in meditation Trends Cogn Sci 200812163ndash169 [PMC free article] [PubMed]

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 29

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30

Page 30: INTEGRACIÓN DE LAS TÉCNICAS MENTE- CUERPO EN SALUD …€¦ · • «Aunque la práctica de la meditación está asociada a una sensación de tranquilidad y relajación física,

Maacutester y Experto en suplementacioacuten nutricional integrativa basado en la evidencia 30