Universidad de Salamanca

Facultad de Biología

Biblioteca

Bionoticias Octubre (4ª) de 2014

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índice

Avisos de la Facultad 4

Biología 6

Biomedicina 10

Biotecnología 13

Neurociencia 21

Células madre y Epigenética 30

.Avisos de la Facultad

SEMINARIO INCYL

”A new computer model of the auditory brainstem response.“

Ponente: Ray Meddis. University of Essex, UK

24 de octubre

12.00 h. en su salón de actos

SEMINARIO CIALE

"Estudio de la ruta de shikimato en Trichoderma parareesei, su papel en

el antagonismo del hongo y en las relaciones que establece con la

planta"

Ponente: Esclaudys Pérez González. Lab. 2 CIALE

Viernes, 31de Octubre de 2014

12,00 horas

Salón de Actos del CIALE

Elegidos los Premios Nacionales de Investigación 2014

La Secretaría de I+D+i ha dado a conocer hoy a los ganadores de los

Premios Nacionales de Investigación 2014. Estos galardones han

distinguido este año a cinco personalidades en las áreas de medicina

.Biología

Cuando ser un buen padre hace aumentar el tamaño del cerebro

Desde no hace mucho, se sabe que un mayor tamaño cerebral está

asociado con un nivel más alto de comportamiento de atención y

cuidados a sus crías por parte de los padres y las madres en numerosos

España destinará más de 12 millones de euros a la adaptación al cambio

climático

El Ministerio de Agricultura, Alimentación y Medio Ambiente

impulsará en 2015 las políticas de adaptación al cambio climático en

España. Susana Magro, directora general de la Oficina Española de

Cómo borran las plantas la memoria del invierno para florecer

Un equipo internacional de científicos europeos y chinos ha descubierto

los mecanismos genéticos que facilitan la floración de las plantas en el

momento adecuado tras los fríos invernales. El autor principal del

Asombrosa técnica para desenrollar ADN

Una manera simple y efectiva de desenredar la masa a menudo

enmarañada del ADN es "enhebrar" la hebra de ADN por un canal

nanométrico. Unos científicos se han valido de simulaciones para

Buscan secuenciar el genoma de un nematodo que afecta al ajo

Además de las plagas, bacterias, hongos y virus que afectan a los

cultivos en general, también debe prestarse atención a los nematodos

fitoparásitos, conocidos como gusanos redondos, capaces de ocasionar

Los niños neandertales tenían menores tasas metabólicas basales y de

crecimiento que los niños actuales

Se acaba de publicar en la revista científica Journal of Human Evolution

un estudio pionero liderado por Ana Mateos, responsable del Grupo de

Paleofisiología del Centro Nacional de Investigación sobre la Evolución

La verdadera enfermedad ósea que padecieron Ramsés II y otros

faraones egipcios

La espondilitis anquilosante es una enfermedad que causa inflamación

en las articulaciones de la columna vertebral y se pensaba que afectó a

diversos miembros de familias de la realeza en el Antiguo Egipto.

Ahora un nuevo estudio rebate esta afirmación, encontrando en su lugar

En busca de los primeros animales

Entrega del podcast Zoo de Fósiles, a cargo de Germán Fernández

Sánchez, en Ciencia para Escuchar, que recomendamos por su interés.

Hace 542 millones de años, comenzó el periodo Cámbrico. El Cámbrico

Comienza la XXVIII Campaña Antártica Española

La XXVIII Campaña Antártica Española ha comenzado hoy con la

salida del Buque de Investigación Oceanográfica Hespérides rumbo a la

Antártida. De los 15 proyectos que se realizarán durante esta campaña,

Las grasas afectan de manera diferente a los cerebros masculino y

femenino

Un grupo interdisciplinar de científicos de instituciones estadounidenses

ha estudiado las diferentes respuestas cerebrales de ratones y ratonas al

comer grasas. El hallazgo, publicado esta semana en la revista Cell

Descubren que una proteína repara el daño causado por el sol en el

ADN

Investigadores del grupo de Melanoma del Vall d’Hebron Institut de

Recerca (VHIR), liderados por Juan Ángel Recio, en España, han

descubierto que la proteína LKB1 es esencial para iniciar el proceso de

Nuevos datos sobre la expansión y la migración del aguilucho lagunero

en el continente europeo

Combinar la información derivada del anillamiento –un método

convencional para estudiar el desplazamiento de las aves– con técnicas

más modernas, como la modelización espacial y el análisis de isótopos

El Museo Virtual de la Vida cuenta con 652 colecciones científicas

El Centro de Investigación y Desarrollo de Recursos Científicos,

Bioscripts, reúne en su plataforma The virtual Museum of Life 652

colecciones científicas repartidas por todo el territorio español para su

Observado el movimiento ultrarrápido de los electrones en una

molécula vital

Científicos de la Universidad Autónoma de Madrid han logrado, por

primera vez, inducir y medir la migración ultrarrápida de carga en una

molécula compleja. Este fenómeno precede cualquier reordenamiento

Los virus de los anfibios aportan claves sobre el contagio entre especies

Un equipo internacional de investigadores, liderado por el Museo

Nacional de Ciencias Naturales, ha estudiado los efectos de un virus del

género Ranavirus, que está diezmando las poblaciones de anfibios del

Los canguros gigantes extintos caminaban en vez de saltar

En 2005 Christine Janis, profesora de ecología y biología evolutiva en la

Universidad de Brown (EE UU), tuvo una intuición al visitar un museo

que albergaba el esqueleto de un estenurino (Sthenurinea), una

El gas natural no ayuda a reducir el efecto invernadero

Frente a quienes defienden que el fracking desplazará al carbón, un

estudio de investigadores estadounidenses indica que un modelo

energético basado en el gas no reducirá las emisiones de gases nocivos

¿Las bacterias usan todo su cuerpo para nadar?

Muchas bacterias nadan utilizando flagelos, apéndices cuya forma

recuerda un poco a la de sacacorchos y que actúan como pequeñas

hélices que empujan a la célula bacteriana o tiran de ella. Desde hace

tiempo, se viene asumiendo que los flagelos realizan todo el trabajo

.Biomedicina

Un hombre paralizado vuelve a caminar tras un trasplante de células

olfativas en su columna

Un equipo de cirujanos polacos y de expertos en regeneración neuronal

de Reino Unido ha llevado a cabo una operación pionera que ha hecho

posible que un hombre con parálisis vuelva a caminar. La intervención

Descubren que una proteína repara el daño causado por el sol en el

ADN

Investigadores españoles han descrito el papel de la proteína

LKB1, que puede ser un factor pronóstico del riesgo de tener cáncer de

piel. Su trabajo, publicado en PLoS Genetics, afirma que los bajos

Las grasas afectan de manera diferente a los cerebros masculino y

femenino

Comer alimentos con alto contenido en grasas genera mayor

inflamación cerebral en machos que en hembras, según revela un

estudio en ratones. Las consecuencias son un mayor riesgo de diabetes y

Diseñan micro y nanopartículas para mejorar los tratamientos de

alzhéimer y párkinson

Investigadores de la Universidad del País Vasco han desarrollado

técnicas de encapsulación para administrar correcta y eficazmente

fármacos. Su objetivo es mejorar los tratamientos del alzhéimer y

Fármacos dirigidos, microchips y terapias personalizadas, nuevas armas

frente al cáncer

Expertos en oncología, entre ellos, el español José Baselga, uno de los

mayores especialistas del mundo en cáncer de mama, se han reunido en

Madrid en el Simposio Internacional sobre el cáncer organizado por la

Fundación Ramón Areces. La medicina personalizada, los

nanomedicamentos y los tratamientos basados en la inmunomodulación

Implantes de células madre curan la ceguera a pacientes con

enfermedades de retina

Un equipo de investigadores estadounidenses ha probado la eficacia de

las células madre para regenerar el tejido del ojo en 18 personas. Los

implantes no han producido rechazo y les han devuelto la vista.

.Biotecnología

La Fundación Bit asiste a la revisión intermedia de la Comisión Europea

del proyecto Inbionet para formar científicos

Su objetivo es la formación de la próxima generación de científicos

europeos en el campo de la inmunología microbiana

Andalucía acogerá un Seminario sobre Biotecnología de Microalgas en

la región Euromediterránea

Se celebra en Almería del 20 al 24 de octubre con el objetivo de conocer

las necesidades para su desarrollo e implantación industrial

ConCiencia, té, comienza esta semana en León

Esta serie de charlas divulgativas sobre Biotecnología tendrá lugar en la

capital leonesa del 8 al 14 de noviembre

Symbiotica, primera plataforma online de formación y divulgación de la

biotecnología

Symbiotica es un proyecto de divulgación online de biotecnología, y

plataforma de formación mediante el uso de TICs englobado dentro de

FEBiotec Divulga.

Genome editing technique advanced by researchers

Customized genome editing -- the ability to edit desired DNA sequences

to add, delete, activate or suppress specific genes -- has major potential

for application in medicine, biotechnology, food and agriculture. Now

Ancient Europeans intolerant to lactose for 5,000 years after they

adopted agriculture

By analyzing DNA from petrous bones of ancient Europeans, scientists

have identified these peoples remained intolerant to lactose (natural

sugar in the milk of mammals) for 5,000 years after they adopted

agricultural practices. The scientific team examined nuclear ancient

DNA extracted from thirteen individuals from burials from

Peanut in house dust linked to peanut allergy in children with skin gene

mutation

A strong link between exposure to peanut protein in household dust

during infancy and the development of peanut allergy in children

genetically predisposed to a skin barrier defect has been discovered by

Norovirus stomach bug: Scientists take step towards drug to treat

An experimental drug currently being trialled for influenza and Ebola

viruses could have a new target: norovirus, often known as the winter

vomiting virus. A team of researchers has shown that the drug,

Tarantula venom illuminates electrical activity in live cells

A cellular probe that combines a tarantula toxin with a fluorescent

compound has been developed to help scientists observe electrical

activity in neurons and other cells. This is the first time researchers have

Once CD8 T cells take on one virus, they'll fight others too

CD8 T cells are known for becoming attuned to fight a specific

pathogen ('adaptive immunity'), but a new study shows that in that

process they also become first-responders that can fend off a variety of

Pharmaceuticals and the water-fish-osprey food web

Ospreys do not carry significant amounts of human pharmaceutical

chemicals, despite widespread occurrence of these chemicals in water, a

recent study finds. These findings represent the first published study

Crystallizing the DNA nanotechnology dream

For the last 20 years, scientists have tried to design large DNA crystals

with precisely prescribed depth and complex features -- a design quest

just fulfilled by scientists. The team built 32 DNA crystals with

Lab-developed intestinal organoids form mature human tissue in mice

Researchers have successfully transplanted 'organoids' of functioning

human intestinal tissue grown from pluripotent stem cells in a lab dish

into mice -- creating an unprecedented model for studying diseases of

Study examines type of exome sequencing, molecular diagnostic yield

In a sample of patients with undiagnosed, suspected genetic conditions,

a certain type of exome sequencing method was associated with a

higher molecular diagnostic yield than traditional molecular diagnostic

First step: From human cells to tissue-engineered esophagus

In a first step toward future human therapies, researchers have shown

that esophageal tissue can be grown in vivo from both human and

mouse cells.

Scientists restore hearing in noise-deafened mice, pointing way to new

therapies

Scientists have restored the hearing of mice partly deafened by noise,

using advanced tools to boost the production of a key protein in their

ears. By demonstrating the importance of the protein, called NT3, in

maintaining communication between the ears and brain, these new

In between red light and blue light: New functionality of molecular light

switches

Diatoms play an important role in water quality and in the global

climate. They generate about one fourth of the oxygen in the Earth’s

atmosphere and perform around one-quarter of the global carbon

New molecule from herb discovered, potential for drug development

A new molecule that can join together chains of amino acids -- the

building blocks of protein -- has been discovered by researchers. Only

three other known molecules have been discovered to be able to

Imaging electric charge propagating along microbial nanowires

Physicists report that they've used a new imaging technique,

electrostatic force microscopy, to resolve the biological debate with

evidence from physics, showing that electric charges do indeed

Mutation associated with cleft palate in humans, dogs identified

Scientists studying birth defects in humans and purebred dogs have

identified an association between cleft lip and cleft palate -- conditions

that occur when the lip and mouth fail to form properly during

High-speed evolution in the lab: Geneticists evaluate cost-effective

genome analysis

Life implies change. And this holds true for genes as well. Organisms

require a flexible genome in order to adapt to changes in the local

environment. Researchers want to know why individuals differ from

How a molecular Superman protects genome from damage

A new role for the RNAi protein Dicer has been found in preserving

genomic stability. Researchers discovered that Dicer helps prevent

collisions during DNA replication by freeing transcription machinery

Misfolded proteins clump together in a surprising place

A surprising finding about the aggregates of misfolded cellular proteins

has been made. Patients with Parkinson's disease, cardiovascular

disease, and cystic fibrosis may have something in common: cells in

Using test tube experiments to study how bacterial species evolve

antibiotic resistance

Given a critical change in the environment, how exactly, do species

adapt? Researchers wanted to get at the heart of this evolutionary

question by measuring the growth rates and DNA mutations of 8

Cellular self-destruct program has deep roots throughout evolution

In what seems like a counter-intuitive move against survival, within

animals, some cells are fated to die from the triggering of an elaborate

cell death program, known as apoptosis. Now, researchers have honed

in on understanding the evolution of caspase-8, a key cell death initiator

Cells' powerhouses were once energy parasites: Study upends current

theories of how mitochondria began

Parasitic bacteria were the first cousins of the mitochondria that power

cells in animals and plants -- and first acted as energy parasites in those

cells before becoming beneficial, according to a new study.

Sugared soda consumption, cell aging associated in new study

Sugar-sweetened soda consumption might promote disease

independently from its role in obesity, according to UC San Francisco

researchers who found in a new study that drinking sugary drinks was

MicroRNA molecules serve as on/off switches for inflammation

Two microRNA molecules that control chronic inflammation have been

found by researchers, a discovery that one day may help researchers

prevent certain fatal or debilitating conditions before they start.

Human genetic research uncovers how omega-6 fatty acids lower bad

cholesterol

Research based on the genetic information from over 100,000

individuals of European ancestry has uncovered a gene that affects

blood cholesterol levels through the generation of a compound from

Cell architecture: Finding common ground

When it comes to cellular architecture, function follows form. Plant

cells contain a dynamic cytoskeleton, which is responsible for directing

cell growth, development, movement, and division. Over time, changes

Are male brains wired to ignore food for sex? Nematode study points to

basic biological mechanisms

Choosing between two good things can be tough. When animals must

decide between feeding and mating, it can get even trickier. In a

discovery that might ring true even for some humans, researchers have

For one family, zebrafish help provide genetic answers

Research in zebrafish has helped identify the cause of an unknown

genetic disorder affecting a boy and two of his uncles, scientists report.

The researchers tracked down a mutation carried only by the affected

males and their mothers, within a gene called RPL10. When the

equivalent gene was suppressed in zebrafish, the animals developed

smaller heads, which is one of the major symptoms of the huma

.Neurociencia

El ictus amenaza también a los jóvenes

En las últimas dos décadas, ha aumentado en un 25% la incidencia de

infartos cerebrales en personas de entre 20 y 64 años. Leer

600.000 niños con retraso intelectual por culpa del plomo

La OMS alerta sobre la contaminación por este metal a través de

pinturas y otros materiales, sobre todo en países pobres. Leer

Smoking interferes with neurocognitive recovery during abstinence

from alcohol

Researchers know that alcohol-dependent individuals (ALC) sustain

neurocognitive impairment even after detoxification. A new study

examines specific domains of cognitive recovery in conjunction with

Fight against Alzheimer's disease: New research on walnuts

An new animal study reveals potential brain-health benefits of a walnut-

enriched diet. Researchers suggest that a diet including walnuts may

have a beneficial effect in reducing the risk, delaying the onset, slowing

Immune proteins moonlight to regulate brain-cell connections

When it comes to the brain, 'more is better' seems like an obvious

assumption. But in the case of synapses, which are the connections

between brain cells, too many or too few can both disrupt brain

Memory decline among menopausal women could be next research

frontier for hypnotic relaxation therapy

Memory decline — a frequent complaint of menopausal women —

potentially could be lessened by hypnotic relaxation therapy, say

researchers who already have done studies showing that such therapy

Tarantula venom illuminates electrical activity in live cells

A cellular probe that combines a tarantula toxin with a fluorescent

compound has been developed to help scientists observe electrical

activity in neurons and other cells. This is the first time researchers have

A rich vocabulary can protect against cognitive impairment

Some people suffer incipient dementia as they get older. To make up for

this loss, the brain's cognitive reserve is put to the test. Researchers have

studied what factors can help to improve this ability and they conclude

Key factor in transition from moderate to problem drinking

A tiny segment of genetic material known as a microRNA plays a

central role in the transition from moderate drinking to binge drinking

and other alcohol use disorders, researchers have discovered.

Mental rest and reflection boost learning, study suggests

A new study, which may have implications for approaches to education,

finds that brain mechanisms engaged when people allow their minds to

rest and reflect on things they've learned before may boost later

See-through sensors open new window into the brain

Developing invisible implantable medical sensor arrays, a team of

engineers has overcome a major technological hurdle in researchers’

efforts to understand the brain. The team has now described its

Scientists restore hearing in noise-deafened mice, pointing way to new

therapies

Scientists have restored the hearing of mice partly deafened by noise,

using advanced tools to boost the production of a key protein in their

ears. By demonstrating the importance of the protein, called NT3, in

User-friendly electronic 'Eyecane' enhances navigational abilities for

blind

White Canes provide low-tech assistance to the visually impaired, but

some blind people object to their use because they are cumbersome, fail

to detect elevated obstacles, or require long training periods to master.

Why your brain makes you reach for junk food

Will that be a pizza for you or will you go for a salad? Choosing what

you eat is not simply a matter of taste, conclude scientists in a new

study. As you glance over a menu or peruse the shelves in a

Heart rate may predict survival, brain function in comatose cardiac

arrest survivors

Patients with sinus bradycardia during therapeutic hypothermia had a 50

to 60 percent lower mortality rate at 180 days than those with no sinus

bradycardia, a study has found. The same research also found that sinus

Improving bladder function among people with spinal cord injuries

New research may lead to dramatically fewer bladder infections

following spinal cord injuries and other traumatic injuries -- infections

that can cause kidney damage, and even death, scientists report.

See-through, one-atom-thick, carbon electrodes powerful tool to study

brain disorders

A graphene, one-atom-thick microelectrode now solves a major

problem for investigators looking at brain circuitry. Pinning down the

details of how individual neural circuits operate in epilepsy and other

Sport in old age can stimulate brain fitness, but effect decreases with

advancing age

Physical exercise in old age can improve brain perfusion as well as

certain memory skills, say neuroscientists who studied men and women

aged between 60 and 77. In younger individuals regular training on a

Brain activity provides evidence for internal 'calorie counter'

As you think about how a food will taste and whether it's nutritious, an

internal calorie counter of sorts is also evaluating each food based on its

caloric density, according to findings from a new neuroimaging study.

Fairness is in the brain, scientists say

Ever wondered how people figure out what is fair? Look to the brain for

the answer. According to a new brain study, people appreciate fairness

in much the same way as they appreciate money for themselves, and

New antidepressant: Rapid agent restores pleasure-seeking ahead of

other antidepressant action

A drug being studied as a fast-acting mood-lifter restored pleasure-

seeking behavior independent of -- and ahead of -- its other

antidepressant effects. Within 40 minutes after a single infusion of

Design of micro, nanoparticles to improve treatments for Alzheimer's,

Parkinson's

Techniques are being developed to deliver correctly and effectively

certain drugs to treat Alzheimer's and Parkinson's. Both disorders affect

Head injury causes immune system to attack brain, new study finds

Scientists have uncovered a surprising way to reduce the brain damage

caused by head injuries -- stopping the body's immune system from

killing brain cells. A new study showed that in experiments on mice, an

Aspirin shown to benefit schizophrenia treatment

Some anti-inflammatory medicines, such as aspirin, estrogen, and

Fluimucil, can improve the efficacy of existing schizophrenia

treatments, new research suggests. Research has shown that the immune

New test to help brain injury victims recover

A new assessment can help patients suffering from traumatic brain

injury, aneurism, dementia, stroke and more between ages 18-74,

experts say. The test is suitable for measuring concentration, memory

Pathological gambling is associated with altered opioid system in the

brain

All humans have a natural opioid system in the brain. Now new

research has found that the opioid system of pathological gamblers

responds differently to those of normal healthy volunteers.

Eating breakfast increases brain chemical involved in regulating food

intake, cravings

Eating breakfast, particularly meals rich in protein, increases young

adults' levels of a brain chemical associated with feelings of reward,

which may reduce food cravings and overeating later in the day.

Action video games bolster sensorimotor skills, study finds

People who play action video games such as Call of Duty or Assassin's

Creed seem to learn a new sensorimotor skill more quickly than non-

gamers do, psychology researchers have found.

How the brain leads us to believe we have sharp vision

We assume that we can see the world around us in sharp detail. In fact,

our eyes can only process a fraction of our surroundings precisely. In a

series of experiments, psychologists have been investigating how the

Presence of enzyme may worsen effects of spinal cord injury and impair

long-term recovery

Traumatic spinal cord injury (SCI) is a devastating condition with few

treatment options. Studies show that damage to the barrier separating

blood from the spinal cord can contribute to the neurologic deficits that

Change your walking style, change your mood

Our mood can affect how we walk -- slump-shouldered if we're sad,

bouncing along if we're happy. Now researchers have shown it works

Scientists find 'hidden brain signatures' of consciousness in vegetative

state patients

Scientists in Cambridge have found hidden signatures in the brains of

people in a vegetative state, which point to networks that could support

consciousness even when a patient appears to be unconscious and

Myelin vital for learning new practical skills

New evidence of myelin's essential role in learning and retaining new

practical skills, such as playing a musical instrument, has been

uncovered by research. Myelin is a fatty substance produced by the

Myth-conceptions: How myths about the brain are hampering teaching

Myths about the brain are common among teachers worldwide and are

hampering teaching, according to new research. The report highlights

several areas where new findings from neuroscience are becoming

Are male brains wired to ignore food for sex? Nematode study points to

basic biological mechanisms

Choosing between two good things can be tough. When animals must

decide between feeding and mating, it can get even trickier. In a

discovery that might ring true even for some humans, researchers have

Male and female brains aren't equal when it comes to fat

Researchers have found that male and female brains respond in

remarkably different ways to high-fat meals. Those differences in the

brain lead to greater inflammation and increased health risks in males

Brain's compass relies on geometric relationships, say researchers

The brain has a complex system for keeping track of which direction

you are facing as you move about; remembering how to get from one

place to another would otherwise be impossible. Researchers have now

Mild traumatic brain injury can have lasting effects for families

Families of patients with mild traumatic brain injury (TBI) may expect

them to return to normal quickly — after all, it's "just a concussion."

But mild TBI can have a lasting impact on families as well as patients,

Single gene links susceptibility to rare infections with predisposition to

autoimmune disease

The mutations were familiar, but the patients’ conditions seemed

baffling at first. A team of researchers had linked variations in an

immune gene to rare bacterial infections. Shortly afterward, Chinese

.Células madre y Epigenética

With three first-in-human trials, therapeutic stem cell science takes a

bold step

Therapeutic stem cell-based science is stepping out of the laboratory

and closer to real-world medical applications. The unprecedented trials

involve potential therapies for spinal cord injuries, Type 1 diabetes and

Lab-developed intestinal organoids form mature human tissue in mice

Researchers have successfully transplanted 'organoids' of functioning

human intestinal tissue grown from pluripotent stem cells in a lab dish

into mice -- creating an unprecedented model for studying diseases of

'Mega' cells control growth of blood-producing cells

While megakaryocytes are best known for producing platelets that heal

wounds, these “mega” cells found in bone marrow also play a critical

role in regulating stem cells according to new research. In fact,

First step: From human cells to tissue-engineered esophagus

In a first step toward future human therapies, researchers have shown

that esophageal tissue can be grown in vivo from both human and

mouse cells.

Stem cells discovered in the esophagus

Despite previous indications to the contrary, the esophagus does have its

own pool of stem cells, say researchers. The findings could lead to new

Cryptic clues drive new theory of bowel cancer development

Researchers have challenged conventional thinking on how the bowel

lining develops and, in the process, suggested a new mechanism for

how bowel cancer starts. The researchers produced evidence that stem

Cell discovery challenges dogma on how fetus develops; holds insights

for liver cancer, regeneration

A new kind of stem cell has been discovered that can become either a

liver cell or a cell that lines liver blood vessels, according to a study.

Using standard tools of molecular biology, the team garnered evidence

Why depression and aging are linked to increased disease risk

New research shows that both aging and depression are associated with

a biochemical change in a gene on chromosome 6, the FKBP5 gene.

This means that we may have found one reason for why risk for aging-

Biblioteca. Facultad de Biología

Universidad de Salamanca. Campus Miguel de Unamuno

c/Donantes de Sangre s/n 37007 Salamanca

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