Post on 21-Apr-2015
ÁCIDOS NUCLÉICOS
Nucleotídeo Nucleotídeo
Unidade Formadora de Ac. Unidade Formadora de Ac. NucléicoNucléico
Bases Nitrogenadas:
Purínicas:
•Adenina
•Guanina
Pirimidínicas:
•Citosina
•Timina
•Uracila
Tipos:
DNA (Ac. Desoxirribonucléico)
RNA (Ac. Ribonucléico)
M P1
M P2
M P3
M P4
M P5
M P6
M P7
M P8
M P9
M P10
M P11
M P12
M P13
M P14
M P15
M P16
M P17
M P18
M P19
M P20
M P21
M P22
M PX Y
= Macho
Coleção CromossômicaColeção Cromossômica
C T G T C A C T C G G G T
G A C AG T G A G C C C A
DNA: ESTRUTURA GERALDNA: ESTRUTURA GERAL
DNA: ESTRUTURA DETALHADADNA: ESTRUTURA DETALHADA
Se a informação genética contida em cada célula nucleada fosse
escrita em um livro,haveriam aproximadamente 500.000 páginas escritas de ambos os lados
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
AATCGATCGATGCCTGTGACTCGATCGAAACTCGACTCGCTCGCTAGATCGACGTAGCACGACTAGCTCCGGGGCTCGAAAACTCTCTGACTACGATCGCTCGCGCTCGCTGGGGAATCCCGCTAGCAACATCGATTCGCGCTAGCTACGCTACCCCTTTGGAAATACAGGGTAATAGCGATCGATGGGATACAGATCGATCATATCGATCGGGAACGCGCCGATAATAAGGATAGCT
C T G T C A C T C G G G T
G A C AG T G A G C C C A
DNA: ESTRUTURA GERALDNA: ESTRUTURA GERAL
Ir p/ primeira página
Organização de um gene
Início da transcrição
ATG (códon de iniciação)Promotor
DNAcromossomal Exon 1 Intron 1 Exon 2 Intron2 Exon3
Códon de terminação
Sítio de adição de Poli-A
Término da transcrição
Transcrito de RNA primárioClivagem por uma
endonuclease
Transcrito de RNA maduro
5’ 3’
AAAAAAAAAAAAA
FLUXO DA EXPRESSÃO GÊNICA
DNA RNA PROTEÍNA
DNA
REPLICAÇÃO:
•Biossíntese de DNA à partirde um molde de DNA
•Ocorre na fase S
•Ocorre no sentido 5’ – 3´•Semi-conservativo
Começa em sítios específicos (Ricos em A e T
• Eucarioto: ~30.000sítios por cromossoma
• Procarioto: Único sítio (OriC)
Replicação:
• Contínua 5’ –3’
• Descontínua (Fragmentos de OKASAKI)
COMPONENTES:
•Helicase
•SSB
•Primer
•Primase
•DNA Polimerase SIGMA
•Topoisomerase
•DNA Ligase
PCR (Polymerize Chain reaction)
•Replicação in vitro
•Aplicação: Diagnóstico molecular de Doenças Genéticas e Infecciosas
CONDIÇÔES DA PCR
Temperatura:•Desnaturação : 95o C
•Anelamento: 60oC
•Corrida: 72oC
Vários Ciclos: 30
Enzima: Taq Polimerase
...T T C G T T C G A T G G A T A A A C C G A...
...A A G C T A C C T A T T T G G C TG G C T...
Reação em Cadeia da PolimeraseReação em Cadeia da Polimerase
Reação em Cadeia da PolimeraseReação em Cadeia da Polimerase
...T T C G T T C G A T G G A T A A A C C G A...
A A G CA A G C
...A A G C T A C C T A T T T G G C TG G C T...
C C G AC C G A
...T T C G T T C G A T G G A T A A A C C G A...
...A A G C T A C C T A T T T G G C TG G C T...
Reação em Cadeia da PolimeraseReação em Cadeia da Polimerase
...T T C G T T C G A T G G A T A A A C C G A...
...A A G C T A C C T A T T T G G C TG G C T...