Año Académico: 2018-2019 ESTRUCTURA …...Estudios Propios 5 3) Ponce M, Ponce J....

Estudios Propios 1

Estudio Propio: EXPERTO EN AVANCES EN EL MANEJO DE LAS ENFERMEDADES DEL ESÓFAGO

Código Plan de Estudios: EN62

Año Académico: 2018-2019

ESTRUCTURA GENERAL DEL PLAN DE ESTUDIOS:

CURSO

Obligatorios Optativos Prácticas Externas

Memoria/ Proyecto

Créditos

Créditos Nº

Asignaturas Créditos

Nº Asignaturas

Créditos Créditos

1º 27 7 27

2º

3º

ECTS TOTALES

27 7 27

PROGRAMA TEMÁTICO:

ASIGNATURAS OBLIGATORIAS

Código Asignatura

Curso Denominación Carácter OB/OP

Créditos

704405 1 DISFAGIA OROFARÍNGEA Y TRASTORNOS DE LA MOTILIDAD ESOFÁGICA

OB 4

704406 1 ENFERMEDAD POR REFLUJO GASTROESOFÁGICO OB 4

704407 1 ESOFAGITIS EOSINOFÍLICA OB 4

704408 1 LESIONES ESOFAGOGÁSTRICAS POR CÁUSTICOS TRAUMATISMOS Y CUERPOS EXTRAÑOS

OB 4

705183 1 CONCEPTOS BÁSICOS: ANATOMOFISIOLOGÍA, FUNCIÓN MOTORA Y PROCEDIMIENTOS PARA EXPLORAR EL ESÓFAGO

OB 4

705184 1 ESOFAGITIS INFECCIOSAS OB 3

705185 1 CÁNCER DE ESÓFAGO OB 4

Carácter: OB - Obligatoria; OP – Optativa

Estudios Propios 2

GUÍA DOCENTE

Año académico 2018-2019

Estudio Experto en Avances en el Manejo Avanzado de las Enfermedades del Esófago (EN62)

Nombre de la asignatura CONCEPTOS BÁSICOS: ANATOMOFISIOLOGÍA, FUNCIÓN MOTORA Y PROCEDIMIENTOS PARA EXPLORAR EL ESÓFAGO

Carácter (Obligatoria/Optativa) OB

Créditos (1 ECTS=25 horas) 4

Modalidad (elegir una opción)

Presencial

Semipresencial

X On-line

Profesor responsable Silvia Delgado Arós

Idioma en el que se imparte Español

DISTRIBUCIÓN DE CRÉDITOS (especificar en horas)

Número de horas presenciales/on-line asistencia profesor 40

Número de horas de trabajo personal del estudiante 60

Total horas 100

CONTENIDOS (Temario)

Tema 1. Anatomía, histología y embriología del esófago. Tema 2. Anomalías en el desarrollo del esófago. Tema 3. Función neuromuscular del esófago. Tema 4. Técnicas y procedimientos para explorar el esófago. Tema 5. Caso clínico: acalasia esofágica. Tema 6. Sesión iconográfica: imágenes comentadas.

EVALUACIÓN

los alumnos deberán realizar una prueba tipo test compuesta por 20 preguntas objetivas y cada pregunta contiene cuatro opciones de respuesta siendo una de ellas la válida. Los criterios de evaluación exigidos para aprobar la asignatura son contestar correctamente el 70% de las preguntas.

BIBLIOGRAFÍA

1) Gomollón F. Manual de Tratamiento de las enfermedades gastroenterológicas de AEG 4º Edición. Elsevier. Barcelona. (Copyright, 2019).

Estudios Propios 3

2) Lacima G. Serra M, Minguez M, Accarinno A. Tratado de Neurogastroenterología y Motilidad Digestiva. Grupo Español de Motilidad Digestiva. Panamericana. Madrid. (Copyright 2016).

3) Ponce M, Ponce J. Anatomofisiología y síntomas de enfermedad esofágica. En: Montoro M & García Pagán JC (eds). Manual de Práctica Clínica de Gastroenterología y Hepatología. Grupo Editorial-CTO. Madrid 2016: 119-34.

4) Marin Fernandez I & Serra J. Técnicas y procedimientos para explorar el esófago. En: Montoro M & García Pagán JC (eds). Manual de Práctica Clínica de Gastroenterología y Hepatología. Grupo Editorial-CTO. Madrid 2016: 135-46

5) Gyawali CP, de Bortoli N, Clarke J, Marinelli C, Tolone S, Roman S, Savarino E. Indications and interpretation of esophageal function testing. Ann N Y Acad Sci. 2018 May 12. doi: 10.1111/nyas.13709.

6) Pandolfino JE, Kahrilas PJ: AGA technical review on the clinical use of esophageal manometry. Gastroenterology 2005;128:209–24

7) Sasegbon A, Hamdy S. The anatomy and physiology of normal and abnormal swallowing in oropharyngeal dysphagia. Neurogastroenterol Motil. 2017;29 (11). doi: 10.1111/nmo.13100. Epub 2017 May 25.

8) Matsuo K, Palmer JB. Anatomy and physiology of feeding and swallowing: normal and abnormal. Phys Med Rehabil Clin N Am. 2008; 19(4):691-707.

9) Shaw SM, Martino R. The normal swallow: muscular and neurophysiological control. Otolaryngol Clin North Am. 2013;46:937-56.

10) Hila A, Castell JA, Castell DO. Pharyngeal and upper esophageal sphincter manometry in the evaluation of dysphagia. J Clin Gastroenterol. 2001; 33(5):355-61.

11) Miller L, Clavé P,, Farré R, Lecea B, Ruggieri MR, Ouyang A et al. Physiology of the upper segment, body, and lower segment of the esophagus. Ann N Y Acad Sci. 2013;1300:261-77.

12) Yazaki E, Sifrim D. Anatomy and physiology of the esophageal body. Dis Esophagus. 2012;25:292-8.

Estudios Propios 4

GUÍA DOCENTE



Nombre de la asignatura DISFAGIA OROFARÍNGEA Y TRASTORNOS DE LA MOTILIDAD ESOFÁGICA.




Presencial

Semipresencial

X On-line

Profesor responsable Fermín Mearín Manrique (DNI 50414742F)





Total horas 100


Tema 1. Disfagia orofaríngea y trastornos de la motilidad esofágica. Tema 2: Caso clínico: dolor torácico de origen esofágico Tema 3: Sesión de videoendoscopia: tratamiento endoscópico de la acalasia Tema 4: Sesión iconográfica. Imágenes comentadas.

EVALUACIÓN

Los alumnos deberán realizar una prueba tipo test compuesta por 20 preguntas objetivas y cada pregunta contiene cuatro opciones de respuesta siendo una de ellas la válida. Los criterios de evaluación exigidos para aprobar la asignatura son contestar correctamente el 70% de las preguntas.

BIBLIOGRAFÍA


2) Lacima G. Serra M, Minguez M, Accarinno A. Tratado de Neurogastroenterología y Motilidad Digestiva. Grupo Español de Motilidad Digestiva. Panamericana. Madrid. (Copyright 2016).

Estudios Propios 5

3) Ponce M, Ponce J. Anatomofisiología y síntomas de enfermedad esofágica. En: Montoro M & García Pagán JC (eds). Manual de Práctica Clínica de Gastroenterología y Hepatología. Grupo Editorial-CTO. Madrid 2016: 119-34.

4) Garrigues Gil V & Ortiz Belver V, Trastornos motores del esófago. En: Montoro N & García Pagán JC (eds). Manual de Práctica Clínica en Gastroenterología y Hepatología. Grupo editorial CTO. Madrid 2016: 163-78.

5) Bill J, Rajagopal S, Kushnir V, Gyawali CP. Diagnostic yield in the evaluation of dysphagia: experience at a single tertiary care center. Dis Esophagus. 201 1;31(6) doi: 10.1093/dote/doy013.

6) Gyawali CP, Savarino E, Lazarescu A, Bor S, Patel A, Dickman R et al. Curriculum for neurogastroenterology and motility training: A report from the joint ANMS-ESNM task force. Neurogastroenterol Motil. 2018 Mar 25:e13341

7) Akinsiku O, Yamasaki T, Brunner S, Ganocy S, Fass R. High resolution vs conventional esophageal manometry in the assessment of esophageal motor disorders in patients with non-cardiac chest pain. Neurogastroenterol Motil. 2018;30(6):e13282.

8) Schlottmann F, Patti MG. Primary Esophageal Motility Disorders: Beyond Achalasia. Int J Mol Sci. 2017 30;18: 1399

9) Rohof WOA, Bredenoord AJ Chicago Classification of Esophageal Motility Disorders: Lessons Learned. Curr Gastroenterol Rep. 2017; 19:37.

10) Kahrilas PJ, Bredenoord AJ, Fox M, Gyawali CP, Roman S, Smout AJ, Pandolfino JE, International High Resolution Manometry Working Group. The Chicago Classification of esophageal motility disorders, v3.0. Neurogastroenterol Motil. 2015;27:160-74.

11) Coss-Adame E, Rao SS. A Review of Esophageal Chest Pain. Gastroenterol Hepatol (N Y). 2015; 11:759-66. 12) Nguyen TM, Eslick GD. Systematic review: the treatment of noncardiac chest pain with antidepressants.

Aliment Pharmacol Ther. 2012; 35:493-500. 13) Coss-Adame E, Erdogan A, Rao SS. Treatment of esophageal (noncardiac) chest pain: an expert review.

Clin Gastroenterol Hepatol. 2014;12:1224-45. 14) Carlson DA, Pandolfino JE. The Chicago criteria for esophageal motility disorders: what has changed in

the past 5 years? Curr Opin Gastroenterol. 2012; 28:395-402. 15) Fox MR, Pandolfino JE, Sweis R, Sauter M, Abreu Y Abreu AT et al. Inter-observer agreement for

diagnostic classification of esophageal motility disorders defined in high-resolution manometry. Dis Esophagus. 2015; 28:711-9.

16) Cho YK, Kim SH. Current Status of Peroral Endoscopic Myotomy. Clin Endosc. 2018;51:13-8. 17) Francis DL, Katzka DA. Achalasia: update on the disease and its treatment. Gastroenterology

2010;139:369-74 18) Stavropoulos SN, Modayil RJ, Friedel D, Savides T. The international per oral endoscopic myotomy survey

(IPOEMS): a snapshot of the global POEM experience. Surg Endosc 2013;27:3322-38. 19) Miranda García P, Casals Seoane F, Gonzalez JM, Barthet M, Santander Vaquero C. Per-oral endoscopic

myotomy (POEM): a new endoscopic treatment for achalasia. Rev Esp Enferm Dig. 2017 Oct;109(10):719-726

20) Eleftheriadis N, Inoue H, Ikeda H, Onimaru M, Maselli R, Santi G. Submucosal tunnel endoscopy: Peroral endoscopic myotomy and peroral endoscopic tumor resection. World J Gastrointest Endosc. 2016 25;8:86-103.

21) Giulini L, Dubecz A, Stein HJ. Laparoscopic Heller myotomy after failed POEM and multiple balloon dilatations : Better late than never. Chirurg. 2017; 88:303-6.

22) Rahden BH, Filser J, Al-Nasser M, Germer CT. Surgical treatment of achalasia - endoscopic or laparoscopic? : Proposal for a tailored approach. Chirurg. 2017 Mar; 88(3):204-210.

Estudios Propios 6

GUÍA DOCENTE



Nombre de la asignatura ENFERMEDAD POR REFUJO GASTROESOFÁGICO.




Presencial

Semipresencial

X On-line

Profesor responsable Carlos Guarner Argente





Total horas 100


Tema 1. Enfermedad por reflujo gastroesofágico. Tema 2. Tratamientos avanzados del esófago de Barrett Tema 3. Caso clínico: pirosis funcional. Tema 4: Vídeoendoscopia: manejo endoscópico avanzado del esófago de Barrett Tema 5. Sesión iconográfica: imágenes comentadas.

EVALUACIÓN


BIBLIOGRAFÍA


2) Alcedo J. Enfermedad por reflujo gastroesofágico. En: Montoro M & García Pagán JC (eds) Manual de Práctica Clínica en Gastroenterología y Hepatología. Grupo editorial CTO. Madrid. 2016: 147-61.

3) Lacima G. Serra M, Minguez M, Accarinno A. Tratado de Neurogastroenterología y Motilidad Digestiva.

Estudios Propios 7

Grupo Español de Motilidad Digestiva. Panamericana. Madrid. (Copyright 2016). 4) Vakil N, van Zanten SV, Kahrilas P, Dent J, Jones R; Global Consensus Group. The Montreal definition and

classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900-20;

5) Savarino E, Bredenoord AJ, Fox M, Pandolfino JE, Roman S, Gyawali CP, International Working Group for Disorders of Gastrointestinal Motility and Function. Expert consensus document: Advances in the physiological assessment and diagnosis of GERD. Nat Rev Gastroenterol Hepatol. 2017; 14:665-76.

6) Gyawali CP, Kahrilas PJ, Savarino E, Zerbib F, Mion F, Smout AJPM et al. Modern diagnosis of GERD: the Lyon Consensus. Gut. 2018; 67:1351-62.

7) Katz PO, Gerson LB, Vela MF. Guidelines for the diagnosis and management of gastroesophageal reflux disease. Am J Gastroenterol. 2013;108:308-28

8) Serra J. Update on gastroesophageal reflux disease. Gastroenterol Hepatol. 2014;37:73-82. 9) Stachler RJ, Francis DO, Schwartz SR, Damask CC, Digoy GP, Krouse HJ et al. Clinical Practice Guideline:

Hoarseness (Dysphonia) (Update) Executive Summary. Otolaryngol Head Neck Surg. 2018;158:409-26. 10) Ates F, Francis DO, Vaezi MF. Refractory gastroesophageal reflux disease: advances and treatment.

Expert Rev Gastroenterol Hepatol. 2014;8:657-67 11) Achem SR, DeVault KR. Gastroesophageal reflux disease and the elderly. Gastroenterol Clin North Am.

2014;43:147-60 12) Keller J. What Is the Impact of High-Resolution Manometry in the Functional Diagnostic Workup of

Gastroesophageal Reflux Disease? Visc Med. 2018 ;34:101-108. 13) Roman S, Holloway R, Keller J, et al.: Validation of criteria for the definition of transient lower esophageal

sphincter relaxations using high-resolution manometry. Neurogastroenterol Motil 2017;29:DOI: 10.1111/ nmo.12920

14) Fox MR, Bredenoord AJ: Oesophageal high-resolution manometry: moving from research into clinical practice. Gut 2008;57:405–23

15) Savarino V, Marabotto E, Zentilin P, Furnari M, Bodini G, De Maria C et al. The appropriate use of proton pump inhibitors. Minerva Med. 2018 May 31. doi: 10.23736/S0026-4806.

16) Cicala M, Emerenziani S, Guarino MP, Ribolsi M. Proton pump inhibitor resistance, the real challenge in gastro-esophageal reflux disease. World J Gastroenterol. 2013 21;19:6529-35

17) Fass R, Sifrim D. Management of heartburn not responding to proton pump inhibitors. Gut. 2009 ; 58:295-309.

18) Del Piano M, Pagliarulo M, Tari R, Carmagnola S, Balzarini M, Lorenzini P, Pane M. Correlation between chronic treatment with proton pump inhibitors and bacterial overgrowth in the stomach: any possible beneficial role for selected lactobacilli? J Clin Gastroenterol. 2014; 48 Suppl 1:S40-6.

19) Vardar R, Keskin M, Valitova E, Bayrakci B, Yildirim E, Bor S. Effect of alginate in patients with GERD hiatal hernia matters. Dis Esophagus. 2017 1; 30:1-7.

20) Clermont M, Falk GW. Clinical Guidelines Update on the Diagnosis and Management of Barrett's Esophagus. Dig Dis Sci. 2018;63:2122-8

21) Amadi C, Gatenby P. Barrett's oesophagus: Current controversies. World J Gastroenterol. 2017 28; 23:5051-67.

22) Wani S, Rubenstein JH, Vieth M, Bergman J. Diagnosis and Management of Low-Grade Dysplasia in Barrett's Esophagus: Expert Review From the Clinical Practice Updates Committee of the America Gastroenterological Association. Gastroenterology. 2016; 151:822-35.

23) Weusten B, Bisschops R, Coron E, Dinis-Ribeiro M, Dumonceau JM, Esteban JM et al. Endoscopic management of Barrett's esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy. 2017; 49:191-198.

24) Nayna L, Emma W, Vani K Radiofrequency ablation for low-grade dysplasia in Barrett's esophagus.Curr Opin Gastroenterol. 2016; 32:294-301.

25) Reyes Genere J, Wang KK Endoscopic techniques for treating gastroesophageal reflux. Curr Opin Gastroenterol. 2018;34:288-94.

26) Triadafilopoulos G. Endoscopic Options for Gastroesophageal Reflux: Where Are We Now and What Does the Future Hold? Curr Gastroenterol Rep.2016; 18:47.

27) Garg SK, Gurusamy KS. Laparoscopic fundoplication surgery versus medical management for gastro-oesophageal reflux disease (GORD) in adults. Cochrane Database Syst Rev. 2015 Nov 5; (11):CD003243. Epub 2015 Nov 5.

Estudios Propios 8

28) Jobe BA, Richter JE, Hoppo T, et al.: Preoperative diagnostic workup before antireflux surgery: an evidence and experience-based consensus of the Esophageal Diagnostic Advisory Panel. J Am Coll Surg 2013;217: 586–597.

29) Maret-Ouda J, Wahlin K, El-Serag HB, Lagergren J. Association Between Laparoscopic Antireflux Surgery and Recurrence of Gastroesophageal Reflux. JAMA. 2017 12; 318:939-46.

30) Kellokumpu I, Voutilainen M, Haglund C, Färkkilä M, Roberts PJ, Kautiainen H. Quality of life following laparoscopic Nissen fundoplication: assessing short-term and long-term outcomes. World J Gastroenterol. 2013 28; 19:3810-8.

31) Fanous M, Jaehne A, Lorenson D, Williams S. Impact of Endoscopic Training for Surgeons on Endolumenal and Laparoscopic Treatment for Gastroesophageal Reflux Disease: Data from a Rural, High-Volume Antireflux Program. Am Surg. 2018 1;84:e245-e247

32) Ota K, Takeuchi T, Harada S, Edogawa S, Kojima Y, Inoue T, Higuchi K. A novel endoscopic submucosal dissection technique for proton pump inhibitor-refractory gastroesophageal reflux disease. Scand J Gastroenterol. 2014; 49:1409-13. Epub 2014 Nov 11

33) Wang YT, Tai LF, Yazaki E, et al.: Investigation of dysphagia after antireflux surgery by high-resolution manometry: impact of multiple water swallows and a solid test meal on diagnosis, management, and clinical outcome. Clin Gastroenterol Hepatol 2015;13:1575–83

34) Brown SR, Gyawali CP, Melman L, et al.: Clinical outcomes of atypical extra-esophageal reflux symptoms following laparoscopic antireflux surgery. Surg Endosc 2011;25:3852–8

Estudios Propios 9

GUÍA DOCENTE



Nombre de la asignatura ESOFAGITIS EOSINOFÍLICA




Presencial

Semipresencial

X On-line

Profesor responsable Alfredo Lucendo Villarín





Total horas 100


Tema 1. Esofagitis eosinofílica. Tema 2. Controversias en el tratamiento de la esofagitis eosinofílica: resumen y actualización de las guías europeas. Tema 5. Caso clínico Tema 6. Encuentro con el patólogo. Tema 7: Sesión iconográfica: imágenes comentadas.

EVALUACIÓN


BIBLIOGRAFÍA


2) Lucendo AJ, Molina-Infante J, Arias Á, von Arnim U, Bredenoord AJ, Bussmann C, et al. Guidelines on eosinophilic esophagitis: evidence-based statements and recommendations for diagnosis and

Estudios Propios 10

management in children and adults. United European Gastroenterol J. 2017; 5:335-58. 3) Chehade M, Lucendo AJ, Achem SR, Souza RF. Causes, evaluation, and consequences of eosinophilic

esophagitis. Ann N Y Acad Sci. 2013; 1300:110-8. 4) Dellon ES, Liacouras CA, Molina-Infante J, Furuta GT, Spergel JM, Zevit N et al. Updated international

consensus diagnostic criteria for eosinophilic esophagitis: Proceedings of the AGREE conference. Gastroenterology. 2018 Jul 12; Epub 2018 Jul 12.

5) Spergel JM, Dellon ES, Liacouras CA, Hirano I, Molina-Infante J, Bredenoord AJ, Furuta GT; participants of AGREE. Summary of the updated international consensus diagnostic criteria for eosinophilic esophagitis: AGREE conference. Ann Allergy Asthma Immunol. 2018 17. pii: S1081-1206(18)30516-7

6) Lucendo AJ, Arias Á, Redondo-González O, Molina-Infante J. Quality assessment of clinical practice guidelines for eosinophilic esophagitis using the AGREE II instrument. Expert Rev Gastroenterol Hepatol. 2017; 11:383-90

7) Cianferoni A, Spergel JM. From genetics to treatment of eosinophilic esophagitis. Curr Opin Allergy Clin Immunol. 2015; 15:417-25.

8) Dowling PJ, Neuhaus H, Polk BI. The Role of the Environment in Eosinophilic Esophagitis. Clin Rev Allergy Immunol. 2018 Jul 21. doi: 10.1007/s12016-018-8697-9.

9) Lynch KL, Dhalla S, Chedid V, Ravich WJ, Stein EM, Montgomery EA, et al. Gender is a determinative factor in the initial clinical presentation of eosinophilic esophagitis. Dis Esophagus. 2016; 29:174-8

10) Talley NJ, Walker MM. The Rise and Rise of Eosinophilic Gut Diseases Including Eosinophilic Esophagitis Is Probably Not Explained by the Disappearance of Helicobacter pylori, so Who or What's to Blame? Am J Gastroenterol. 2018 Jul;113(7):941-944.

11) Ribaldone DG. Eosinophilic esophagitis and celiac disease. Minerva Gastroenterol Dietol. 2018 May 31. doi: 10.23736/S1121-421X.18.02504-7.

12) Pellicano R, De Angelis C, Ribaldone DG, Fagoonee S, Astegiano M.2013 update on celiac disease and eosinophilic esophagitis. Nutrients. 201322; 5:3329-36

13) Ludvigsson JF, Aro P, Walker MM, Vieth M, Agréus L, Talley NJ et al. Celiac disease, eosinophilic esophagitis and gastroesophageal reflux disease, an adult population-based study. Scand J Gastroenterol. 2013; 48:808-14

14) Egan M, Atkins D.What Is the Relationship Between Eosinophilic Esophagitis (EoE) and Aeroallergens? Implications for Allergen Immunotherapy. Curr Allergy Asthma Rep. 2018 16;18:43.

15) Exercise-induced chest pain: an atypical manifestation of eosinophilic esophagitis. Kahn J, Bussmann C, Beglinger C, Straumann A, Hruz P. Am J Med. 2015; 128:196-9.

16) Achem SR, Almansa C, Krishna M, Heckman MG, Wolfsen HC, Talley NJ et al. Oesophageal eosinophilic infiltration in patients with noncardiac chest pain. Aliment Pharmacol Ther. 2011; 33:1194-201.

17) Ram G, Lee J, Ott M, Brown-Whitehorn TF, Cianferoni A, Shuker M et al. Seasonal exacerbation of esophageal eosinophilia in children with eosinophilic esophagitis and allergic rhinitis. Ann Allergy Asthma Immunol. 2015; 115:224-8.

18) Corning B, Copland AP, Frye JW. The Esophageal Microbiome in Health and Disease. Curr Gastroenterol Rep. 2018 1;20:39.

19) Safroneeva E, Saner C, Rossel JB, Golay D, Pittet V, Godat S et al (Swiss EoE Cohort Study Group). Cohort Profile: The Swiss Eosinophilic Esophagitis Cohort Study (SEECS). Inflamm Intest Dis 2018;2:163-70.

20) Goyal A. Eosinophilic esophagitis: short and long-term considerations. Curr Opin Pediatr. 2018 Jul 14. doi: 10.1097/MOP.0000000000000662

21) Ko E, Chehade M. Biological Therapies for Eosinophilic Esophagitis: Where Do We Stand? Clin Rev Allergy Immunol. 2018 Jan 25;

22) Schoepfer A, Safroneeva E, Straumann A. Eosinophilic Esophagitis: Impact of Latest Insights Into Pathophysiology on Therapeutic Strategies. Dig Dis. 2016; 34:462-8.

23) Cheng E, Souza RF, Spechler SJ. Tissue remodeling in eosinophilic esophagitis. Am J Physiol Gastrointest Liver Physiol. 2012 1; 303(11):G1175-87.

24) Eskian M, Khorasanizadeh M, Assa'ad AH, Rezaei N. Monoclonal Antibodies for Treatment of Eosinophilic Esophagitis. Clin Rev Allergy Immunol. 2018; 55:88-98.

25) Spergel J, Aceves SS. Allergic components of eosinophilic esophagitis. J Allergy Clin Immunol. 2018 ;142:1-8

26) Molina-Infante J, Prados-Manzano R, Gonzalez-Cordero PL. The role of proton pump inhibitor therapy in the management of eosinophilic esophagitis. Expert Rev Clin Immunol. 2016 ; 12: 45-52.

27) Wen T, Dellon ES, Moawad FJ, Furuta GT, Aceves SS, Rothenberg ME. Transcriptome analysis of proton pump inhibitor-responsive esophageal eosinophilia reveals proton pump inhibitor-reversible allergic inflammation. J Allergy Clin Immunol. 2015; 135:187-97.

Estudios Propios 11

28) Lieberman JA. Are there different subtypes of eosinophilic esophagitis? Ann Allergy Asthma Immunol. 2018 Jun 1. pii: S1081-1206(18)30389-2.

29) Ma C, van Rhijn BD, Jairath V, Nguyen TM, Parker CE, Aceves SS et al. Heterogeneity in Clinical, Endoscopic, and Histologic Outcome Measures and Placebo Response Rates in Clinical Trials of Eosinophilic Esophagitis: A Systematic Review. Clin Gastroenterol Hepatol. 2018 Jun 13. pii: S1542-3565(18)30610-4.

30) Gutiérrez-Junquera C, Fernández-Fernández S, Cilleruelo ML, Rayo A, Román E. The Role of Proton Pump Inhibitors in the Management of Pediatric Eosinophilic Esophagitis. Front Pediatr. 2018 May 8;6:119. doi: 10.3389/fped.2018.00119.

31) Greuter T, Safroneeva E, Bussmann C, Biedermann L, Vavricka SR, Katzka DA et al. Maintenance Treatment of Eosinophilic Esophagitis With Swallowed Topical Steroids Alters Disease Course Over A 5-Year Follow-Up Period in Adult Patients. Clin Gastroenterol Hepatol. 2018 11. pii: S1542-3565(18)30598-6.

Estudios Propios 12

GUÍA DOCENTE



Nombre de la asignatura LESIONES ESOFAGOGÁSTRICAS POR CÁUSTICOS,

TRAUMATISMOS Y CUERPOS EXTRAÑOS




Presencial

Semipresencial

X On-line

Profesor responsable Joan Tosca Cuquerella





Total horas 100


Tema 1. Lesiones esofagogástricas por cáusticos. Tema 2. Traumatismos y cuerpos extraños. Tema 3. Manejo endoscópico y quirúrgico de las lesiones por cáusticos. Tema 4. Abordaje endoscópico del cuerpo extraño. Tema 5. Caso clínico: lesiones por cáusticos. Tema 6. Sesión iconográfica. Imágenes comentadas.

EVALUACIÓN


BIBLIOGRAFÍA

1) Zargar SA, Kochhar R, Mehta S, Mehta SK. The role of fiberoptic endoscopy in the management of corrosive ingestion and modified endoscopic classification of burns. Gastrointest Endosc 1991;37:165-9

Estudios Propios 13

2) Cowan T, Foster R, Isbister GK Acute esophageal injury and strictures following corrosive ingestions in a 27 year cohort. Am J Emerg Med. 2017;35:488-92

3) Bird JH, Kumar S, Paul C, Ramsden JD Controversies in the management of caustic ingestion injury: an evidence-based review. Clin Otolaryngol. 2017; 42:701-8.

4) Kurowski JA, Kay M. Caustic Ingestions and Foreign Bodies Ingestions in Pediatric Patients. Pediatr Clin North Am. 2017; 64:507-24.

5) Ozdemir R, Bayrakci B, Tekşam O, Yalçin B, Kale G. Thirty-three-year experience on childhood poisoning. Turk J Pediatr 2012;54:251-9

6) Urganci N, Usta M, Kalyoncu D, Demirel E. Corrosive substance ingestion in children. Indian J Pediatr 2014;81:675-9

7) Doğan Y, Erkan T, Cokuğraş FC, Kutlu T. Caustic gastroesophageal lesions in childhood: an analysis of 473 cases. Clin Pediatr (Phila) 2006;45:435-8.

8) Le Naoures P, Hamy A, Lerolle N, Métivier E, Lermite E, Venara A. Risk factors for symptomatic esophageal stricture after caustic ingestion-a retrospective cohort study. Dis Esophagus 2017 1;30:1-6

9) Nunes AC, Romãozinho JM, Pontes JM, Rodrigues V, Ferreira M, Gomes D, Freitas D. Risk factors for stricture development after caustic ingestion. Hepatogastroenterology. 2002; 49:1563-6

10) Kochhar R, Ashat M, Reddy YR, Dhaka N, Manrai M, Sinha SK et al. Relook endoscopy predicts the development of esophageal and antropyloric stenosis better than immediate endoscopy in patients with caustic ingestion. Endoscopy. 2017; 49:643-50

11) Ertekin C, Alimoglu O, Akyildiz H, Guloglu R, Taviloglu K. The results of caustic ingestions Hepatogastroenterology. 2004;51:1397-400

12) Mamede RC, de Mello Filho FV. Ingestion of caustic substances and its complications. Sao Paulo Med J. 2001 4;119:10-5.

13) Kikendall JW. Caustic ingestion injuries. Gastroenterol Clin North Am. 1991; 20:847-57. 14) Vandenplas Y.Management of Benign Esophageal Strictures in Children. Pediatr Gastroenterol Hepatol

Nutr. 2017;20:211-5 15) Bruzzi M, Chirica M, Resche-Rigon M, Corte H, Voron T, Sarfati E et al. Emergency Computed Tomography

Predicts Caustic Esophageal Stricture Formation. Ann Surg. 2018 Mar 12. doi: 10.1097/SLA.0000000000002732

16) Bonnici KS, Wood DM, Dargan PI. Should computerised tomography replace endoscopy in the evaluation of symptomatic ingestion of corrosive substances? Clin Toxicol (Phila). 2014; 52:911-25

17) Lurie Y, Slotky M, Fischer D, Shreter R, Bentur Y.The role of chest and abdominal computed tomography in assessing the severity of acute corrosive ingestion. Clin Toxicol (Phila). 2013; 51:834-7.

18) Losada M M, Rubio M M, Blanca G JA, Pérez A C. Ingestion of caustic substances in children: 3 years of experience. Rev Chil Pediatr. 2015;86:189-93

19) Núñez O, González-Asanza C, de la Cruz G, Clemente G, Bañares R, Cos E, Menchén P Study of predictive factors of severe digestive lesions due to caustics ingestion. Med Clin (Barc). 2004 6; 123:611-4

20) Nuutinen M, Uhari M, Karvali T, Kouvalainen K. Consequences of caustic ingestions in children. Acta Paediatr. 1994;83:1200-5.

21) Riffat F, Cheng A. Pediatric caustic ingestion: 50 consecutive cases and a review of the literature. Dis Esophagus. 2009; 22:89-94.

22) Rodríguez MA, Meza Flores JL. Clinical-epidemiological characteristics in caustics ingestion patients in the Hipólito Unanue National Hospital.Rev Gastroenterol Peru. 2003; 23:115-25.

23) Boskovic A, Stankovic I. Predictability of gastroesophageal caustic injury from clinical findings: is endoscopy mandatory in children? Eur J Gastroenterol Hepatol. 2014;26:499-503

24) Temiz A, Oguzkurt P, Ezer SS, Ince E, Hicsonmez A. Predictability of outcome of caustic ingestion by esophagogastroduodenoscopy in children. World J Gastroenterol. 2012 14;18:1098-103

25) Poley JW, Steyerberg EW, Kuipers EJ, Dees J, Hartmans R, Tilanus HW, Siersema PD Ingestion of acid and alkaline agents: outcome and prognostic value of early upper endoscopy. Gastrointest Endosc. 2004; 60:372-7.

26) Temiz A, Oguzkurt P, Ezer SS, Ince E, Hicsonmez A. Long-term management of corrosive esophageal stricture with balloon dilation in children. Surg Endosc. 2010; 24:2287-92.

27) Ilkin Naharci M, Tuzun A, Erdil A, Ates Y, Bagci S, Yamanel L, Dagalp K. Effectiveness of bougie dilation for the management of corrosive esophageal strictures. Acta Gastroenterol Belg. 2006; 69:372-6.

28) de Jong AL, Macdonald R, Ein S, Forte V, Turner A. Corrosive esophagitis in children: a 30-year review. Int J Pediatr Otorhinolaryngol. 2001; 57:203-11

29) Gün F, Abbasoğlu L, Celik A, Salman ET. Early and late term management in caustic ingestion in children: a 16-year experience. Acta Chir Belg. 2007;107:49–52

Estudios Propios 14

30) Gaudreault P, Parent M, McGuigan MA, Chicoine L, Lovejoy FH. Predictability of esophageal injury from signs and symptoms: a study of caustic ingestion in 378 children. Pediatrics. 1983;71:767–70

31) Betalli P, Falchetti D, Giuliani S, Pane A, Dall’Oglio L, de Angelis GL, Caldore M, Romano C, Gamba P, Baldo V. Caustic ingestion in children: is endoscopy always indicated? The results of an Italian multicenter observational study. Gastrointest Endosc. 2008;68:434–9

32) Broto J, Asensio M, Jorro CS, Marhuenda C, Vernet JM, Acosta D, Ochoa JB. Conservative treatment of caustic esophageal injuries in children: 20 years of experience. Pediatr Surg Int. 1999;15:323–5

33) Ulman I, Mutaf O. A critique of systemic steroids in the management of caustic esophageal burns in children. Eur J Pediatr Surg. 1998;8:71–4.

34) Usta M, Erkan T, Cokugras FC, Urganci N, Onal Z, Gulcan M, et al. High doses of methylprednisolone in the management of caustic esophageal burns. Pediatrics 2014;133:E1518-24

35) Divarci E, Celtik U, Dokumcu Z, Ozcan C, Erdener A. The efficacy of intralesional steroid injection in the treatment of corrosive esophageal strictures in children Surg Laparosc Endosc Percutan Tech 2016;26:e122-5.

36) Berger M, Ure B, Lacher M. Mitomycin C in the therapy of recurrent esophageal strictures: hype or hope? Eur J Pediatr Surg 2012;22:109-16.

37) Jayakrishnan VK, Wilkinson AG. Treatment of oesophageal strictures in children: a comparison of fluo

roscopically guided balloon dilatation with surgical bouginage. Pediatr Radiol 2001;31:98-101 38) Arévalo-Silva C, Eliashar R, Wohlgelernter J, Elidan J, Gross M. Ingestion of caustic substances: a 15-year

experience. Laryngoscope. 2006;116:1422–6 39) Kamijo Y, Kondo I, Kokuto M, Kataoka Y, Soma K. Miniprobe ultrasonography for determining prognosis in

corrosive esophagitis. Am J Gastroenterol. 2004;99:851–4 40) Baskin D, Urganci N, Abbasoğlu L, Alkim C, Yalçin M, Karadağ C, Sever N. A standardised protocol for the

acute management of corrosive ingestion in children. Pediatr Surg Int. 2004;20:824–8 41) Ciftci AO, Senocak ME, Büyükpamukçu N, Hiçsönmez A. Gastric outlet obstruction due to corrosive

ingestion: incidence and outcome. Pediatr Surg Int. 1999;15:88–91 42) Kaushik R, Singh R, Sharma R, Attri AK, Bawa AS. Corrosive-induced gastric outlet obstruction. Yonsei Med

J. 2003;44:991–4 43) Tekant G, Eroğlu E, Erdoğan E, Yeşildağ E, Emir H, Büyükünal C, Yeker D. Corrosive injury-induced gastric

outlet obstruction: a changing spectrum of agents and treatment. J Pediatr Surg. 2001;36:1004–7 44) Coopman S, Michaud L, Halna-Tamine M, Bonnevalle M, Bourgois B, Turck D, et al. Long-term outcome of

colon interposition after esophagectomy in children. J Pediatr Gastroenterol Nutr 2008;47:458-62. 45) Lee JH. Foreign Body Ingestion in Children. Clin Endosc. 2018; 51:129-36. 46) ASGE Standards of Practice Committee; Ikenberry SO, Jue TL, Anderson MA, Appalaneni V, Banerjee S,

Ben-Menachem T, Decker GA, Fanelli RD, Fisher LR, et al: Management of ingestedforeign bodies and food impactions. Gastrointest Endosc 2011;73: 1085-91

47) Blanco-Rodríguez G, Teyssier-Morales G, Penchyna-Grub J, Madriñan-Rivas JE, Rivas-Rivera IA, Trujillo-Ponce de León A et al. Características y resultados de la ingestión de cuerpos extraños en niños. Arch Argent Pediatr. 2018 1;116:256-61.

48) Sink JR, Kitsko DJ, Mehta DK, et al. Diagnosis of pediatric foreign body ingestion: clinical presentation, physical examination, and radiologic finding. An Otol Rhinol Laryngol 2016; 125:342-50

49) Yuan F, Tang X, Gong W, Su L, Zhang Y. Endoscopic management of foreign bodies in the upper gastrointestinal tract: An analysis of 846 cases in China. Exp Ther Med. 2018;15:1257-62

50) Li ZS, Sun ZX, Zou DW, Xu GM, Wu RP and Liao Z: Endoscopic management of foreign bodies in the upper-GI tract: Experience with 1088 cases in China. Gastrointest Endosc 2006; 64: 485-92

51) Anderson KL and Dean AJ: Foreign bodies in the gastrointestinal tract and anorectal emergencies. Emerg Med Clin North Am 2011; 29:369-400

52) Chiu YH, Hou SK, Chen SC, How CK, Lam C, Kao WF, Yen DH and Huang MS: Diagnosis and endoscopic management of upper gastrointestinal foreign bodies. Am J Med Sci 2012; 343: 192-5

53) Jayachandra S, Eslick G. A systematic review of paediatric foreign body ingestion: presentation, complications, and management. Int J Pediatr Otorhinolaryngol 2013; 77:311-7.

54) Kay M, Wyllie R. Pediatric foreign bodies and their management. Curr Gastroenterol Rep. 2005;:212-8 55) Tringali A, Thomson M, Dumonceau JM, et al. Pediatric gastrointestinal endoscopy: European Society of

Gastrointestinal Endoscopy (ESGE) and European Society for Paediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) Guideline Executive summary. Endoscopy 2017; 49:83-91

56) Vicari JJ, Johanson JF and Frakes JT: Outcomes of acute esophageal food impaction: Success of the push technique. Gastrointest Endosc 2001; 53: 178-81

57) Kimball SJ, Park AH, Rollins MD 2nd, et al. A review of esophageal disc battery ingestions and a protocol

Estudios Propios 15

for management. Arch Otolaryngol Head Neck Surg 2010; 136:866-71. 58) Chen T, Wu HF, Shi Q, Zhou PH, Chen SY, Xu MD et al. Endoscopic management of impacted esophageal

foreign bodies. Dis Esophagus; 26:799-806. 59) Hong KH, Kim YJ, Kim JH, Chun SW, Kim HM, Cho JH. Risk factors for complications associated with upper

gastrointestinal foreign bodies. World J Gastroenterol. 2015; 14; 21:8125-31. 60) Blanco Rodríguez G, PenchynaGrub J, Ochoa Guajardo PL, et al. ¿Que tan urgente es extraer una pila de

disco alojada en el esófago? Bol Med Hosp Infant Mex 2008; 65:282-9 61) Ofosu A, Ramai D, Reddy M. Overtube-Assisted Foreign Body Removal: A Review of Endoscopic

Management and Case Illustration. Cureus 2017 29; 9:e1730. 62) Kim HU. Oroesophageal Fish Bone Foreign Body. Clin Endosc. 2016; 49:318-26 63) Krom H, Visser M, Hulst JM, Wolters VM, Van den Neucker AM, de Meij T et al. Serious complications after

button battery ingestion in children. Eur J Pediatr. 2018;177:1063-70 64) Leinwand K, Brumbaugh DE, Kramer RE. Button Battery Ingestion in Children: A Paradigm for Management

of Severe Pediatric Foreign Body Ingestions. Gastrointest Endosc Clin N Am. 2016; 26:99-118. 65) Shen JY, Zhang HW, Fan KJ, Liao H, Zhang EY, Hu J. Aortoesophageal fistula and arch pseudoaneurysm

after removing of a swallowed chicken bone: a case report of one-stage hybrid treatment. BMC Surg. 2018 11;18:3.

66) Kelly SL, Peters P, Ogg MJ, Li A, Smithers BM. Successful management of an aortoesophageal fistula caused by a fish bone--case report and review of literature. J Cardiothorac Surg. 2009 8; 4:21

67) Toma EA, Oun M, Enciu O, Calu V, Miron A. The Surgical Management of Acute Esophageal Perforation by Accidentally Ingested Fish Bone. Chirurgia (Bucur). 2018;113:156-61.

68) Wang J, Wu WB, Chen L, Zhu Q . Video-mediastinoscopy assisted fish bone extraction and superior Medistinal abscess debridement.. J Cardiothorac Surg. 2018 15;13:38

69) Shimizu K, Otani Y, Nakano T, Takayasu Y, Yasuoka Y, Morishita Y.Successful video-assisted mediastinoscopic drainage of descending necrotizing mediastinitis. Ann Thorac Surg. 2006; 81:2279-81.

70) Singhal P, Kejriwal N, Lin Z, Tsutsui R, Ullal R. Optimal surgical management of descending necrotising mediastinitis: our experience and review of literature. Heart Lung Circ. 2008; 17:124-8.

71) Bayarri Lara CI, Sevilla López S, Sánchez-Palencia Ramos A, Alkourdi Martínez A, Hernández Escobar F, Quero Valenzuela F et al. Cir Esp. 2013; 91:579-83. Surgical management of descending necrotizing mediastinitis.

Estudios Propios 16

GUÍA DOCENTE



Nombre de la asignatura ESOFAGITIS INFECCIOSAS




Presencial

Semipresencial

X On-line

Profesor responsable Miguel Montoro Huguet





Total horas 75


Tema 1. Esofagitis infecciosas. Tema 2. Diagnóstico endoscópico, microbiológico e histopatológico de las infecciones del esófago. Tema 3. Caso clínico. Tema 4. Imágenes comentadas.

EVALUACIÓN


Estudios Propios 17

BIBLIOGRAFÍA

1) Cortés L. Bernal V. Esofagitis infecciosas. En: Montoro M & García Pagán JC (eds) Manual de Emergencias en Gastroenterología y Hepatología. Jarpyo Editores. Madrid. 2013:23-30

2) Bonacini M, Young T, Laine L. The causes of esophageal symptoms in human immunodeficiency virus infection. A prospective study of 110 patients. Arch Intern Med 1991; 151:1567-72.

3) Raufman JP. Odynophagia/dysphagia in AIDS. Gastroenterol Clin North Am. 1988; 17:599-614. 4) Wilcox CM.Esophageal disease in the acquired immunodeficiency syndrome: etiology, diagnosis, and

management. Am J Med. 1992; 92:412-21 5) Ahuja NK, Clarke JO. Evaluation and Management of Infectious Esophagitis in Immunocompromised and

Immunocompetent Individuals. Curr Treat Options Gastroenterol. 2016;14:28-38 6) Al Anazi AR. Gastrointestinal opportunistic infections in human immunodeficiency virus disease. Saudi J

Gastroenterol. 2009;15:95-9. 7) Wilcox CM, Karowe MW. Esophageal infections: etiology, diagnosis, and management. Gastroenterologist.

1994; 2:188-206. 8) Werneck-Silva AL, Pagliari C, Patzina RA, Takakura CFH, Duarte MI. Esophageal mucosa in HIV infection:

A"deeper" look at this little spoken organ. J Gastroenterol Hepatol. 2017;32:1832-8. 9) Frieling T. Non-Cardiac Chest Pain. Visc Med. 2018 ;34:92-6. 10) Sangeorzan JA, Bradley SF, He X, Zarins LT, Ridenour GL, Tiballi RN, et al. Epidemiology of oral candidiasis

in HIV-infected patients: colonization, infection, treatment, and emergence of fluconazole resistance. Am J Med 1994; 97: 339-46

11) Kanda N, Yasuba H, Takahashi T, Mizuhara Y, Yamazaki S, Imada Y, et al. Prevalence of esophageal candidiasis among patients treated with inhaled fluticasone propionate. Am J Gastroenterol 2003; 98: 2146-8

12) Bonacini M, Young T, Laine L. The causes of esophageal symptoms in human immunodeficiency virus infection. A prospective study of 110 patients. Arch Intern Med 1991; 151:1567-72

13) Pappas PG, Kauffman CA, Andes D, Benjamin DK Jr, Calandra TF, Edwards JE Jr, et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009; 48: 503-35

14) Fidel PL Jr. Candida-host interactions in HIV disease: relationships in oropharyngeal candidiasis. Adv Dent Res. 2006 1; 19:80-4.

15) Pons V, Greenspan D, Debruin M. Therapy for oropharyngeal candidiasis in HIV-infected patients: randomized, prospective multicenter study of oral fluconazole versus clotrimazole troches. The Multicenter Study Group. J Acquir Immune Defic Syndr 1993; 6: 1311-6.

16) Canalejo Castrillero E, Garcia Duran F, Cabello N, Garcia Martinez J. Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature. Medicine (Baltimore) 2010; 89: 204-10.

17) McBane RD, Gross JB Jr. Herpes esophagitis: clinical syndrome, endoscopic appearance, and diagnosis in 23 patients. Gastrointest Endosc 1991; 37: 600-3

18) Wilcox CM, Rodgers W, Lazenby A. Prospective comparison of brush cytology, viral culture, and histology for the diagnosis of ulcerative esophagitis in AIDS. Clin Gastroenterol Hepatol 2004; 2: 564-7.

19) Lemonovich TL, Watkins RR. Update on cytomegalovirus infections of the gastrointestinal system in solid organ transplant recipients. Curr Infect Dis Rep 2012; 14: 33-40.

20) Whitley RJ, Jacobson MA, Friedberg DN et al. Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA. Arch Intern Med 1998; 158: 957-69

21) Gravito-Soares E, Gravito-Soares M, Camacho E, Tomé L. Cytomegalovirus ulcerative oesophagitis in a young healthy immunocompetent patient. BMJ Case Rep. 2018 Mar 5;2018. pii: bcr-2017-223297

22) A case of cytomegalovirus infection with splenic infarction and an esophageal ulcer in an immunocompetent adult.

23) Shimizu Y, Komura T, Seike T, Nakai R, Omura H, Kagaya T et al. A case of cytomegalovirus infection with splenic infarction and an esophageal ulcer in an immunocompetent adult. Nihon Shokakibyo Gakkai Zasshi. 2017; 114:1269-76.

24) Laguna F, Garcia-Samaniego J, Alonso MJ, Alvarez I, Gonzalez-Lahoz JM.Pseudotumoral appearance of cytomegalovirus esophagitis and gastritis in AIDS patients. Am J Gastroenterol. 1993;88:1108-11.

25) Kumar S, Minz M, Sinha SK, Vaiphei K, Sharma A, Singh S, Kenwar DB. Esophageal tuberculosis with coexisting opportunistic infections in a renal allograft transplant recipient. Transpl Infect Dis. 2017;19.

26) Perdomo JA, Naomoto Y, Haisa M, Yamatsuji T, Kamikawa Y, Tanaka N.Tuberculosis of the esophagus. Dis Esophagus. 2017 1;11:72-4.

Estudios Propios 18

27) Lozano AS, Leibovich N, Souto G, Sabatini C, Brodersen C, Segal E. Esophageal tuberculosis: case report and review of the literature.Acta Gastroenterol Latinoam. 2011; 41:47-51

28) Aydin A, Tekin F, Ozutemiz O, Musoglu A.Value of endoscopic ultrasonography for diagnosis of esophageal tuberculosis: report of two cases.Dig Dis Sci. 2006; 51:1673-6.

29) Anazawa R, Suzuki M, Miwa H, Miki Y, Tomita K, Nakamura H. A case of esophageal and intestinal tuberculosis that occurred during treatment of rheumatoid arthritis with etanercept. Kekkaku. 2014 ;89:711-6.

30) Mou Y, Zeng H, Wang QM, Yi H, Liu W, Wen D, Hu B. Esophageal tuberculosis initially misdiagnosed by endoscopy as a submucosal tumor. Endoscopy. 2015;47 Suppl 1 UCTN:E30-1. doi: 10.1055/s-0034-1391133.

31) Vahid B, Huda N, Esmaili A. An unusual case of dysphagia and chest pain in a non-HIV patient: esophageal tuberculosis. Am J Med. 2007; 120:e1-2

32) Ni B, Lu X, Gong Q, Zhang W, Li X, Xu H, Zhang S, Shao Y. Surgical outcome of esophageal tuberculosis secondary to mediastinal lymphadenitis in adults: experience from single center in China J Thorac Dis. 2013;5:498-505.

33) Jain SK, Jain S, Jain M, Yaduvanshi A. Esophageal tuberculosis: is it so rare? Report of 12 cases and review of the literature. Am J Gastroenterol. 2002; 97:287-91.

34) Mbiine R, Kabuye R, Lekuya HM, Manyillirah W.Tuberculosis as a primary cause of oesophageal stricture: a case report. J Cardiothorac Surg. 2018 5; 13:58

35) Rana SS, Bhasin DK, Rao C, Srinivasan R, Singh K.Tuberculosis presenting as Dysphagia: clinical, endoscopic, radiological and endosonographic features. Endosc Ultrasound. 2013; 2:92-5.

36) Hajong R, Topno N, Baruah AJ, Das R. Tubercular esophagocutaneous fistula. Indian J Surg. 2013; 75(Suppl 1):6-8.

37) Sharma V, Rana SS, Chhabra P, Sharma R, Gupta N, Bhasin DK. Primary esophageal tuberculosis mimicking esophageal cancer with vascular involvement. Endosc Ultrasound. 2016; 5:61-2.

38) Rana SS, Bhasin DK, Sharma V, Chaudhary V, Singh K. Dysphagia as the first manifestation of tuberculosis. Endoscopy. 2011;43(Suppl 2 UCTN):E300–1

39) Rathinam S, Kanagavel M, Tiruvadanan BS, Santhosam R, Chandramohan SM. Dysphagia due to tuberculosis. Eur J Cardiothorac Surg. 2006;30:833–6

40) Mokoena T, Shama DM, Ngakane H, Bryer JV. Oesophageal tuberculosis: a review of eleven cases. Postgrad Med J. 1992;68:110–5

41) Peixoto PC, Ministro PS, Sadio AD, Cancela EM, Araújo RN, Machado JL et al. Esophageal tuberculosis: an unusual cause of dysphagia. Gastrointest Endosc. 2009;69:1173–6.

42) Aydin A, Tekin F, Ozutemiz O, Musoglu A. Value of endoscopic ultrasonography for diagnosis of esophageal tuberculosis: report of two cases. Dig Dis Sci. 2006;51:1673–6

43) Park JH, Kim SU, Sohn JW, Chung IK, Jung MK, Jeon SW et al. Endoscopic findings and clinical features of esophageal tuberculosis. Scand J Gastroenterol. 2010;45:1269–72

44) Newman RM, Fleshner PR, Lajam FE, Kim U. Esophageal tuberculosis: a rare presentation with hematemesis. Am J Gastroenterol. 1991;86:751-5.

45) Franco J, Gisbert J, Cabañes M, Flores J, Sánchez S, Alegre J. Esophageal tuberculosis and massive hematemesis. An Med Interna. 1990; 7:192-4.

Estudios Propios 19

GUÍA DOCENTE



Nombre de la asignatura CÁNCER DE ESÓFAGO




Presencial

Semipresencial

X On-line

Profesor responsable Joaquín Cubiella Fernández





Total horas 100


Tema 1. Tumores del esófago. Tema 2. Alternativas en el manejo del cáncer de esófago localmente avanzado y del cáncer de esófago inoperable. Tema 3. Sesión de videoendoscopia. Tema 4. Sesión iconográfica: Imágenes comentadas.

EVALUACIÓN


BIBLIOGRAFÍA

1) Fernández Esparrach G. Baiges Aznar A. Visa Turmo L, Castells A. Cáncer de esófago. Em: Montoro M & García Pagán JC (eds). Manual de Práctica Clínica en Gastroenterología y Hepatología. AEG. Grupo Editorial CTO. Madrid. 2016: 197-210.

2) Alexander W. American Society of Clinical Oncology. P T. 2018;43:493-7. 3) Javle M, Hsueh CT. Updates in Gastrointestinal Oncology - insights from the 2008 44th annual meeting of

Estudios Propios 20

the American Society of Clinical Oncology. J Hematol Oncol. 2009; 23; 2:9 4) Yu ZC, Wei C, Xiong F, Wang LS, Yao J. Esophageal cancer-related multiple primary cancers (MPCs). Asian J

Surg. 2018 3. pii: S1015-9584(18)30346-4 5) Domper Arnal MJ, Ferrández Arenas Á, Lanas Arbeloa Á. Esophageal cancer: Risk factors, screening and

endoscopic treatment in Western and Eastern countries. World J Gastroenterol. 2015 14;21:7933-43 6) Rees JR, Lao-Sirieix P, Wong A, Fitzgerald RC. Treatment for Barrett's oesophagus. Cochrane Database Syst

Rev. 2010 Jan 20; (1):CD004060. 7) Altorki NK, Lee PC, Liss Y, Meherally D, Korst RJ, Christos P, Mazumdar M, Port JL. Multifocal neoplasia and

nodal metastases in T1 esophageal carcinoma: implications for endoscopic treatment. Ann Surg. 2008; 247:434-9.

8) Larghi A, Lightdale CJ, Memeo L, Bhagat G, Okpara N, Rotterdam H. EUS followed by EMR for staging of high-grade dysplasia and early cancer in Barrett's esophagus. Gastrointest Endosc. 2005; 62:16-23.

9) Shaheen NJ, Spechler SJ. Total endoscopic eradication of Barrett's esophagus: study methodology, candidate selection, and clinical outcomes. Endoscopy. 2008; 40:994-9.

10) Krugmann J, Vieth M, Neumann H. Barrett's neoplasia: where is the problem?. Zentralbl Chir. 2014; 139:386-92

11) di Pietro M, Canto MI, Fitzgerald RC. Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Screening, Diagnosis, and Therapy. Gastroenterology. 2018; 154:421-36.

12) Curvers WL, Bansal A, Sharma P, Bergman JJ. Endoscopic work-up of early Barrett's neoplasia. Endoscopy. 2008; 40:1000-7.

13) Peerally MF, Bhandari P, Ragunath K, Barr H, Haidry R, Lovat L et al. Radiofrequency ablation compared with argon plasma coagulation after endoscopic resection of high-grade dysplasia or T1 adenocarcinoma in Barrett's esophagus: a randomized pilot study (BRIDE). Gastrointest Endosc. 2018 Aug 1. pii: S0016-5107(18)32898-0.

14) Gatenby P, Bhattacharjee S, Wall C, Caygill C, Watson A. Risk stratification for malignant progression in Barrett's esophagus: Gender, age, duration and year of surveillance. World J Gastroenterol. 201628; 22:10592-600

15) Macías-García F, Domínguez-Muñoz JE. Update on management of Barrett's esophagus. World J Gastrointest Pharmacol Ther. 201 6; 7:227-34.

16) Offman J, Muldrew B, O'Donovan M, Debiram-Beecham I, Pesola F, Kaimi I et al. Barrett's oESophagus trial 3 (BEST3): study protocol for a randomised controlled trial comparing the Cytosponge-TFF3 test with usual care to facilitate the diagnosis of oesophageal pre-cancer in primary care patients with chronic acid reflux. BMC Cancer. 2018 3;18:784

17) Manner H, Neugebauer A, Scharpf M, Braun K, May A, Ell C, Fend F, Enderle MD. The tissue effect of argon-plasma coagulation with prior submucosal injection (Hybrid-APC) versus standard APC: A randomized ex-vivo study. United European Gastroenterol J. 2014; 2:383-90

18) Shaheen NJ, Sharma P, Overholt BF, Wolfsen HC, Sampliner RE, Wang KK, et al. Radiofrequency ablation in Barrett’s esophagus with dysplasia. N Engl J Med 2009; 360: 2277–88.

19) Haidry RJ, Butt MA, Dunn J, Banks M, Gupta A, Smart H et al. Radiofrequency ablation for early oesophageal squamous neoplasia: Outcomes from United Kingdom registry. World J Gastroenterol 2013; 19: 6011–9.

20) Phoa KN, van Vilsteren FG, Weusten BL, Bisschops R, Schoon EJ, Ragunath K et al. Radiofrequency ablation vs endoscopic surveillance for patients with Barrett esophagus and low-grade dysplasia: A randomized clinical trial. JAMA 2014; 311: 1209–17.

21) Shaheen NJ, Overholt BF, Sampliner RE, Wolfsen HC, Wang KK, Fleischer DE, et al. Durability of radiofrequency ablation in Barrett’s esophagus with dysplasia. Gastroenterology 2011; 141: 460–8.

22) van Vilsteren FG, Alvarez Herrero L, Pouw RE, ten Kate FJ, Visser M, Seldenrijk CA, et al. Radiofrequency ablation for the endoscopic eradication of esophageal squamous high grade intraepithelial neoplasia and mucosal squamous cell carcinoma. Endoscopy 2011; 43: 282–90.

23) He S, Bergman J, Zhang Y, Weusten B, Xue L, Qin X et al. Endoscopic radiofrequency ablation for early esophageal squamous cell neoplasia: Report of safety and effectiveness from a large prospective trial.

24) Wang WL, Chang IW, Chen CC, Chang CY, Mo LR, Lin JT et al. Radiofrequency ablation versus endoscopic submucosal dissection in treating large early esophageal squamous cell neoplasia. Medicine 2015; 94: e2240.

25) Wang WL, Chang IW, Chen CC, Chang WL, Chu YY, Wu PH et al. Predictors for postoperative esophageal stricture after balloon-based radiofrequency ablation for early esophageal squamous neoplasia: A multicenter validation study. Therap Adv Gastroenterol 2016; 9: 257–264.

26) Scholvinck DW, Alvarez Herrero L, Visser M, Bergman JJ, Weusten BL et al. Effects of Lugol staining on

Estudios Propios 21

stenosis formation induced by radiofrequency ablation of esophageal squamous epithelium: A study in a porcine model. Dis Esophagus 2015; 28: 603–11.

27) Alsop BR, Sharma P. Esophageal Cancer. Gastroenterol Clin North Am. 201; 45:399-412. 28) Knabe M, May A, Ell C. Endoscopic therapy in early adenocarcinomas (Barrett's cancer) of the esophagus. J

Dig Dis. 2015; 16:363-9. 29) Chennat J, Konda VJ, Ross AS, de Tejada AH, Noffsinger A, Hart J et al. Complete Barrett's eradication

endoscopic mucosal resection: an effective treatment modality for high-grade dysplasia and intramucosal carcinoma--an American single-center experience. Am J Gastroenterol. 2009 Nov; 104(11):2684-92.

30) Tan A, Macrae F. Management of cancer risk in Barrett's esophagus. J Gastroenterol Hepatol. 2011; 26:1485-92.

31) Schlottmann F, Patti MG. Current Concepts in Treatment of Barrett's Esophagus With and Without Dysplasia. J Gastrointest Surg. 201; 21:1354-60

32) Udagawa H, Ueno M. Comparison of two major staging systems of esophageal cancer-toward more practical common scale for tumor staging. Ann Transl Med. 2018;6:76.

33) Guo J, Li CQ, Li M, Zuo XL , Yu T , Liu JW et al. Diagnostic value of probe based confocal laser endomicroscopy and high-definition virtual chromoendoscopy in early esophageal squamous neoplasia. Gastrointest Endosc 2015; 81: 1346–54.

34) Dong Z, Wang J, Zhan T, Xu S. Identification of prognostic risk factors for esophageal adenocarcinoma using bioinformatics analysis. Onco Targets Ther. 2018 25;11:4327-337

35) Puli SR, Reddy JB, Bechtold ML, Antillon D, Ibdah JA, Antillon MR et al. Staging accuracy of esophageal cancer by endoscopic ultrasound: A metaanalysis and systematic review. World J Gastroenterol 2008; 14: 1479–90.

36) Yen TJ, Chung CS, Wu YW, Yen RF, Cheng MF, Lee JM, et al. Comparative study between endoscopic ultrasonography and positron emission tomography-computed tomography in staging patients with esophageal squamous cell carcinoma. Dis Esophagus 2012; 25: 40–47.

37) Chen SB, Huang SJ, Liu DT, Weng HR, Chen YP. Clinicopathological features and prognosis of esophageal squamous cell carcinoma in young patients. Dis Esophagus. 2018 Aug 1. doi: 10.1093/dote/doy070.

38) Yin H, Li D, Zhu C, Wang M, Wei N. Factors relevant to the prognosis of patients with esophageal cancer who received intensity-modulated radiotherapy. Thorac Cancer. 2018 Aug 1. doi: 10.1111/1759-7714.12800.

39) Sun NN, Liu C, Ge XL, Wang J. Dynamic contrast-enhanced MRI for advanced esophageal cancer response assessment after concurrent chemoradiotherapy. Diagn Interv Radiol. 2018;24:195-202

40) Tanaka Y, Yoshida K, Suetsugu T, Imai T, Matsuhashi N, Yamaguchi K. Recent advancements in esophageal cancer treatment in Japan. Ann Gastroenterol Surg. 2018;2:253-65

41) Kato H, Nakajima M. Treatments for esophageal cancer: a review. Gen Thorac Cardiovasc Surg. 2013;61:330-5.

42) Nakajima M, Kato H. Treatment options for esophageal squamous cell carcinoma. Expert Opin Pharmacother. 2013; 14:1345-54.

43) Kidane B, Ali A, Sulman J, Wong R, Knox JJ, Darling GE. Health-related quality of life measure distinguishes between low and high clinical T stages in esophageal cancer. Ann Transl Med. 2018;6:270

44) Aujesky R, Neoral C, Kral V, Bohanes T, Vrba R, Vomackova K. Video-assisted laparoscopic resection of the esophagus for carcinoma after neoadjuvant therapy Hepatogastroenterology. 2009; 56:1035-8.

45) Wu B, Xue L, Qiu M, Zheng X, Zhong L, Qin X, Xu Z. J Video-assisted mediastinoscopic transhiatal esophagectomy combined with laparoscopy for esophageal cancer. Cardiothorac Surg. 2010 31; 5:132.

46) Nevala-Plagemann C, Francis S, Cavalieri C, Tao R, Whisenant J, Glasgow R et al. Benefit of adjuvant chemotherapy based on lymph node involvement for oesophageal cancer following trimodality therapy. ESMO Open. 2018 25;3(5):e000386.

47) Yang H, Liu H, Chen Y, Zhu C, Fang W, Yu Z et al. Neoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial. J Clin Oncol. 2018; 8:JCO2018791483.

48) Chiu PW, Chan AC, Leung SF, Leong HT, Kwong KH, Li MK et al. Multicenter prospective randomized trial comparing standard esophagectomy with chemoradiotherapy for treatment of squamous esophageal cancer: early results from the Chinese University Research Group for Esophageal Cancer (CURE). J Gastrointest Surg. 2005; 9:794-802.

49) Jin J, Liao Z, Zhang Z, Ajani J, Swisher S, Chang JY, et al. Induction chemotherapy improved outcomes of patients with resectable esophageal cancer who received chemoradiotherapy followed by surgery. Int J Radiat Oncol Biol Phys. 200 1; 60:427-36.

50) Fujita H, Sueyoshi S, Tanaka T, Toh U, Mine T, Sasahara H et al. New trends in neoadjuvant

Estudios Propios 22

chemoradiotherapy for locally-advanced esophageal cancer: esophagectomy--is it necessary?. Gan To Kagaku Ryoho 2000; 27:2016-22

51) Tang H, Tan L, Shen Y, Wang H, Lin M, Feng Met al. CMISG1701: a multicenter prospective randomized phase III clinical trial comparing neoadjuvant chemoradiotherapy to neoadjuvant chemotherapy followed by minimally invasive esophagectomy in patients with locally advanced resectable esophageal squamous cell carcinoma (cT3-4aN0-1M0) (NCT03001596). BMC Cancer. 2017; 28; 17:450

52) Chen Y, Hao D, Wu X, Xing W, Yang Y, He C et al. Neoadjuvant versus adjuvant chemoradiation for stage II-III esophageal squamous cell carcinoma: a single institution experience. Dis Esophagus. 20171; 30:1-7.

53) Krug S, Michl P Esophageal Cancer: New Insights into a Heterogenous Disease. Digestion. 2017; 95:253-261

54) Peng L, Han YT, Wang X, Xiao WG, Chen LH. Application of artificial pneumothorax in semi-prone position to the video-assisted thoracic surgery of esophageal carcinoma. Zhonghua Zhong Liu Za Zhi. 2012;34:785-9.

55) Shridhar R, Imani-Shikhabadi R, Davis B, Streeter OA, Thomas CR Jr. Curative treatment of esophageal cancer; an evidenced based review. J Gastrointest Cancer. 2013; 44:375-84.

56) Miyata H, Yamasaki M, Kurokawa Y, Takiguchi S, Nakajima K, Fujiwara Y et al. Multimodal treatment for resectable esophageal cancer. Gen Thorac Cardiovasc Surg. 2011; 59:461-6

57) Zhu H, Yang X, Ding Y, Liu J, Lu J, Zhan L et al. Recombinant human endostatin enhances the radioresponse in esophageal squamous cell carcinoma by normalizing tumor vasculature and reducing hypoxia. Sci Rep. 2015 28; 5:14503.

58) Fujita H. History of lymphadenectomy for esophageal cancer and the future prospects for esophageal cancer surgery. Surg Today. 2015;45:140-9.

59) Hiranyatheb P, Osugi H. Radical lymphadenectomy in esophageal cancer: from the past to the present. Dis Esophagus. 2015;28:68-77.

60) Kakegawa T. The history of surgical treatment for esophageal carcinoma in the 20th century in Japan]. Nihon Geka Gakkai Zasshi 2000; 101:847-54.

61) Fujita H. President's address of the 65th annual scientific meeting of the Japanese Association for Thoracic Surgery: challenges for advanced esophageal cancer. Gen Thorac Cardiovasc Surg. 2013; 61:201-7.

62) Lerut T, Nafteux P, Moons J, Coosemans W, Decker G, De Leyn P et al. Three-field lymphadenectomy for carcinoma of the esophagus and gastroesophageal junction in 174 R0 resections: impact on staging, disease-free survival, and outcome: a plea for adaptation of TNM classification in upper-half esophageal carcinoma. Ann Surg. 2004;240: 962-72

63) Law S, Wong J. Lymph node dissection in surgical treatment of esophageal neoplasms. Surg Oncol Clin N Am. 2007; 16:115-31.

64) Chen SB, Weng HR, Wang G, Liu DT, Li H et al. The impact of adjuvant radiotherapy on radically resected T3 esophageal squamous cell carcinoma. J Cancer Res Clin Oncol. 2016; 142:277-86

65) Sunde B, Johnsen G, Jacobsen AB, Glenjen NI, Friesland S, Lindblad M et al. Effects of neoadjuvant chemoradiotherapy vs chemotherapy alone on the relief of dysphagia in esophageal cancer patients: secondary endpoint analysis in a randomized trial. Dis Esophagus. 201 1. doi: 10.1093/dote/doy069.

66) Wang WL, Chang IW, Chen CC, Chang CY, Tseng CH, Tai CM et al. The in vivo tissue effect of endoscopic balloon-based radiofrequency ablation in treating esophageal squamous cell neoplasia. United European Gastroenterol J. 2018;6:656-61.

67) Kawamoto T, Nihei K, Sasai K, Karasawa K. Palliative radiotherapy and chemoradiotherapy in stage IVA/B esophageal cancer patients with dysphagia. Int J Clin Oncol. 2018 Jul 31. doi: 10.1007/s10147-018-1324-1.

68) Akl FM, Elsayed-Abd-Alkhalek S, Salah T. Palliative concurrent chemoradiotherapy in locally advanced and metastatic esophageal cancer patients with dysphagia. Ann Palliat Med. 2013;2:118-23

69) Wong SK, Chiu PW, Leung SF, Cheung KY, Chan AC, Au-Yeung AC ert al. Concurrent chemoradiotherapy or endoscopic stenting for advanced squamous cell carcinoma of esophagus: a case-control study. Ann Surg Oncol. 2008; 15:576-82.

70) Suzuki G, Yamazaki H, Aibe N, Masui K, Tatekawa K, Sasaki Net al. Palliative Radiotherapy in the Local Management of Stage IVB Esophageal Cancer: Factors Affecting Swallowing and Survival. Anticancer Res. 201; 37:3085-3092.

71) Maebayashi T, Ishibashi N, Aizawa T, Sakaguchi M, Taku H, Ohhara M et al. A long-surviving patient with advanced esophageal basaloid squamous cell carcinoma treated only with radiotherapy: case report and literature review. BMC Gastroenterol. 2017 8; 17:151.

Año Académico: 2018-2019 ESTRUCTURA …...Estudios Propios 5 3) Ponce M, Ponce J....

Documents

Transcript of Año Académico: 2018-2019 ESTRUCTURA …...Estudios Propios 5 3) Ponce M, Ponce J....