2 GAMETOGENESIS
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GAMETOGENESIS
Dr. Roberto Aráuz SalgueraMédico Cirujano Diabetólogo
Histo- embriologo
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GAMETOGENESIS
• TEMA No 2 GAMETOGÉNESIS• FOE : CONFERENCIA• MÉTODO: ELABORACIÓN CONJUNTA• OBJETIVOS• 1. Analizar los factores que intervienen en la formación de los gametos masculinos y
femeninos.• 2. Destacar la importancia de la Meiosis durante el proceso de Gametogénesis.• 3.- Explicar la gametogénesis sus relaciones con los defectos y sus implicaciones
legales• CONTENIDO• INTRODUCCIÓN• I. FASES DE LA GAMETOGENESIS• 1. Origen extraembrionario de las células germinales y su migración hacia las gónadas• 2. Aumento en el número de células germinales por Mitosis• 3. Reducción de cromosomas por Meiosis• 4. Maduración estructural y Funcional de los gametos masculinos y femeninos:• 5.- Anormalidades
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1.- ORIGEN EXTRAEMBRIONARIO DE LAS CGP
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2.- MITOSIS
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COMPARACION OVOGENESIS - ESPERMATOGENESIS
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ESPERMATOGÉNESIS
10 spermatocytes
20 spermatocytes (with intercellular bridges)
spermatids
spermatozoa
Spermatogonia (outside the blood-testis barrier)
Sertoli cells
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ESPERMIOGÉNESISESPERMIOGÉNESIS
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3.- MEIOSIS
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4.- OVOGENESIS
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4.- OVOGENESIS
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OVOGENESIS
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OOVOGÉNESISPrimary oocyte
Granulosa cells
Oogonium 1o Oocyte Secondary oocyte
During prophase of meiosis I at the dictyotene stage, lasting from foetal life to the after puberty.
2. At metaphase in the 2o Oocyte prior to ovulation.
Graafian follicle
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ESPERMATOGENESIS
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5.- DISYUNCION (NORMAL) Y NO DISYUNCION (SINDROMES)
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TRISOMÍA 21 (SÍNDROME DE DOWN)
Chromosome 21 in gametogenesis
Trisomy 21 Monosomy 21
(b) Non-disjunction in meiosis I (a) Normal
Normal
Oogonium / Spermatogonium Primary oocyte /spermatocyte(meiosisI) Secondary oocyte /spermatocyte(meiosis II) Ovum / spermatids
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DOTACION CROMOSOMICA DEL NUEVO SER (EJ. VARON)
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COMBINACION DE CROMOSOMAS