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Escuela de VeranoEscuela de VeranoEnero 2014Enero 2014

COMUNICACIN, DINAMISMO Y SEALIZACIONCOMUNICACIN, DINAMISMO Y SEALIZACION

Hctor Contreras M., Hctor Contreras M., PhDPhDPrograma de Fisiologa y BiofsicaPrograma de Fisiologa y BiofsicaInstituto de Ciencias BiomdicasInstituto de Ciencias Biomdicas

Facultad de Medicina. Universidad de ChileFacultad de Medicina. Universidad de ChileEE--mail: hcontrer@med.uchile.clmail: hcontrer@med.uchile.cl

CellCell--surface receptor or intracellular receptor surface receptor or intracellular receptor Forms of intracellular signalingForms of intracellular signaling

Signaling via gap junctionSignaling via gap junction

Multiple extracellular signalsMultiple extracellular signals

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azcares de enlace unidades repetitivas

SO4

Xyl - Gal - Gal - GlcUA - (GlcUA - GalNAc)nSer

Condroitn sulfatoQueratn sulfato Acido hialurnicoDermatn sulfatoHeparn sulfato

Estructura general de los Proteoglucanos

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How gene transcription is activated by a rise in cyclic AMP concentrationHow gene transcription is activated by a rise in cyclic AMP concentration